A Salem Gopi Hospitals Publication

Free Kidney Health FAQ Book in English and Tamil

Dr. Jones Ronald & Dr. Hari Janakiraman

Contents

  1. •Forewordp.1
  2. •About the Authorsp.2
  3. 1.Introductionp.3
  4. 2.Kidney and its Functionsp.4
  5. 3.Types of Kidney Diseasesp.6
  6. 4.Acute Kidney Failure (AKI) — Causes, Symptoms & Treatmentp.22
  7. 5.Chronic Kidney Disease (CKD) — Causes, Symptoms & Preventionp.29
  8. 6.Chronic Kidney Disease Treatmentp.45
  9. 7.Myths about Kidney Disease — Explanationsp.54
  10. 8.Dialysis & Types of Dialysisp.62
  11. 9.Kidney Transplant Surgeryp.75
  12. 10.Nephrotic Syndromep.88
  13. 11.Polycystic Kidney Diseasep.94
  14. 12.Urinary Tract Infectionp.100
  15. 13.The Difference between Nephrology and Urologyp.106
  16. 14.Urologyp.110
  17. 15.Benign Prostate Hyperplasiap.118
  18. 16.Basic Laboratory Tests for Kidney Damage and Surgeryp.124
  19. 17.Food Habitsp.132
  20. 18.Frequently Asked Questionsp.145

Foreword

We are very happy to publish this book on urinary disorders in a question-and-answer format.

During this period we have been witnessing the increasing incidence of kidney diseases — and you will have felt it too. Although kidney diseases are most often caused by diabetes and high blood pressure, there are other important reasons as well. Keeping in mind that we all need to be aware of these, this book has been created. So that everyone can understand it easily, we have written it in simple language, in a question-and-answer style.

This book covers diseases, their causes, early symptoms, precautions to be taken, lifestyle changes and treatments — all in a nutshell, and easy to understand. Common doubts about these conditions, and their explanations, are compiled here.

We hope this small effort will help you know the facts about kidney problems and live a healthy life.

With love,
Dr. Jones Ronald — BSc, MD, MNAMS, DM (Nephrology)
Dr. Hari Janakiraman — MD, DNB (Nephrology)

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About the Authors

Dr. Jones Ronald — BSc, MD, MNAMS, DM (Nephrology)

Dr. Jones Ronald studied Internal Medicine at Tirunelveli Medical College, completed General Medicine at Madurai Medical College, and his postgraduate qualification in Urology at Madurai Medical College. Since then he has worked in Salem as a nephrologist for over 35 years.

He served as the Head of Urology at Kumaramangalam Medical College. After retirement he continues as a urologist at Salem VIMS Hospital and as a urology consultant at Salem Gopi Hospital. He is passionately involved in creating awareness about kidney disorders through magazines, brochures, television and FM radio, has lectured at many international medical seminars, and has received a Lifetime Achievement Award as a urology-care consultant. Drawing on this experience, he has played a key role in publishing this book in a way that everyone can read and understand easily.

Dr. Hari Janakiraman — MD, DNB (Nephrology)

Dr. Hari Janakiraman has more than 15 years of experience as a consultant nephrologist and kidney-transplant consultant. Trained at Manipal Hospital, Bangalore, he is currently Consultant in Nephrology and Kidney Transplantation at Salem Gopi Hospital. He has addressed kidney disorders in medical seminars and is keenly involved in creating awareness through television and radio.

He also has expertise in brain-death declaration and organ donation, and conducts awareness programmes in schools, colleges, institutions and the police department. The first declaration of brain death and organ donation in Salem took place under his supervision. Drawing on this experience, he has advised on the urinary disorders covered in this book.

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Chapter 1

Chapter 1

Introduction

1.1 The renal system consists of:

  1. A pair of kidneys
  2. Urinary tracts
  3. Bladder
  4. Urethra drains urine from bladder.

The Kidneys produce urine. Two Urinary tubes carry urine to the bladder. Urinary bladder saves the urine until it empties. Then urine is excreted from the bladder through the urethra at required intervals.

Human Renal System — Video Guide
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Chapter 2

Chapter 2

Kidney and its Functions

2.1 What is kidney?

The kidneys are a pair of large kidney-shaped organs located on either side of your spine below your ribs and behind your stomach. Each kidney is roughly the size of a large knee.

2.2 What is the size and weight of the kidney?

Common size:

  • Length of kidney is 10 - 12 cm
  • Width of kidney is 4 - 7 cm
  • The width of the kidney is 2 - 4 cm

Weight:

  • Male kidney weighs 125-170 grams.
  • Women Kidney weighs 115-155 grams.

2.3 What are the functions of the kidney?

  1. Removal of waste products from the body
  2. Balancing fluids and minerals in the body
  3. Maintaining blood pressure.
  4. Assist in the production of red blood cells.
  5. Maintaining strong healthy bones with the help of vitamin D.

2.4 How to improve kidney function?

  • It is good to drink enough water.
  • Keep your blood sugar levels under control
  • Monitor and control your blood pressure
  • Engage in regular exercise.
  • It is best to maintain a healthy weight
  • Avoid smoking and drinking alcohol
  • Do not take pain relievers without doctor's advice
  • Adequate sleep is good for health
  • Keep visiting your doctor for regular check-ups
  • Follow the kidney diet procedure properly.

2.5 Who is most likely to develop kidney disease?

If you have kidney problems, you may be at risk of developing chronic kidney disease.

Diabetes
High blood pressure
Heart disease
A family history of kidney disease
Existing disorders of the kidney
Disorders of the renal (urinary) system
Elderly people, and long-term users of over-the-counter painkillers
Kidney & Its Functions — Video Guide
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Chapter 3

Chapter 3

Types of Kidney Diseases

3.1 What is kidney disease?

Kidney disease means that your kidneys are not working properly. Kidney failure is usually temporary. This problem can be corrected if proper treatment is provided. This is what we call acute kidney injury (AKI).

Chronic kidney disease is when your kidneys slowly fail over time. This is what we call Chronic Kidney Disease (CKD). Both high blood pressure and diabetes are major causes of chronic permanent kidney damage.

If this chronic kidney disease is detected early, it can be prevented from worsening with medical intervention. If the damage is too much, then dialysis or kidney transplantation is required.

3.2 How to diagnose kidney failure?

  • Urinalysis:

A microscopic examination of the urine, including a count of red and white blood cells, high levels of bacteria and tissue molds, and a urine sediment test to detect tubular particles are required.

  • Measurements of urine volume:

A simple way to diagnose kidney failure is by measuring how much urine you pass each day.

  • Protein in urine:

Measurement of protein excretion in the urine is essential for renal impairment. This can be determined by the protein-creatinine ratio or by testing the amount of protein in a 24-hour urine sample.

  • Blood test:

Your doctor may suggest blood tests to measure blood urea, and creatinine. A rapid and excessive increase in these levels may indicate acute renal failure.

  • *Shadow images:

Ultrasound, CT-scans and MRI tests can help identify blockages or other problems by imaging the condition of your kidneys and urinary tract.

  • Urinary tissue examination:

Clinical examination of tissue samples is necessary for all types of urinary tract infections. This is called a biopsy. Your doctor may perform a kidney biopsy to collect a tissue sample and examine it closely to accurately predict kidney damage.

  • Special Tests:

Kidney disorders require special blood tests and genetic testing.

3.3 How many types of kidney failure are there?

Kidney failure can be divided into five categories:

  1. Pre-Renal Failure:

Pre-renal failure occurs when there is insufficient blood flow to the kidneys. When the necessary blood flow is reduced, the kidneys are unable to filter toxins from the blood. Therefore, the toxic substances increase in the blood. Diagnosing and correcting the cause of the decreased blood flow can usually cure this type of kidney failure.

  1. Acute Kidney Disease:

This is referred to as acute kidney injury or acute kidney injury. This urinary tract infection can be caused by many reasons. It can be caused by injury to the kidneys due to an accident. Mainly, if the blood flow to the kidneys is obstructed then the kidneys lose their ability to work.

For example, it can be caused due to excessive blood loss due to injury, low blood pressure in the body due to various reasons, blockage in the blood vessels leading to the kidneys and glomerulonephritis, which can be called acute kidney disease. It can also affect kidney function and interstitial tissue.

Besides this, Kidney failure can also be caused by harmful substances, i.e. Toxins. These can be toxic substances produced by the body's toxins, or poisonous substances from outside (Snake venom) - Poison of snakes - (Toxic Medications).

  1. Chronic Prerenal Failure:

If the blood supply to the kidneys is low for a long period of time, there is a risk that the kidneys will shrink and lose their efficiency.

  1. Chronic Internal Renal Failure:

This condition called Chronic Kidney Disease (CKD) is not only very dangerous but also requires constant intensive care. It is caused by kidney diseases that can cause long-term kidney failure.

  1. Post Renal Failure:

It can be caused by any obstruction in the urinary tract. If kidney stones or tumors block the flow of urine for a long time, there is a possibility of gradual pressure on the kidneys and kidney failure.

3.4 What are the differences between chronic kidney disease (CKD) and acute kidney

injury (AKI)?

  • Chronic kidney disease (CKD) is caused by kidney damage lasting more than 3 months, resulting in decreased filtering capacity of the glomerulus. This type of kidney disease is characterized by proteinuria, casts and kidney shrinkage on scan and, if necessary, kidney biopsy. Mainly long-term diseases like diabetes and high blood pressure are the cause of these chronic kidney diseases. This is permanent kidney failure and requires continuous dialysis or dialysis Patients with this disease have symptoms such as nausea, decreased urination, and low urine output, but may not have any symptoms.

Acute kidney injury (AKI) is a condition that usually develops in about 7 to 14 days. It often happens within 7 days, when the kidneys' ability to filter waste quickly decreases. This leads to higher levels of substances like urea and creatinine in the blood, along with imbalances in important minerals called electrolytes.

The good news is that if the cause of the kidney problem is found and fixed, the kidneys can often return to normal. For example, if someone is dehydrated, drinking more fluids can help. If the damage is due to harmful substances, removing those substances can also help the kidneys recover.

However, if there's too much fluid in the body, serious electrolyte imbalances, or very high levels of creatinine in the blood, a temporary treatment called dialysis may be necessary to help the kidneys.

3.5 How many stages are there in chronic renal failure?

Chronic kidney disease (CKD) is categorized into five stages, depending on how well your kidneys are able to filter waste products and excess fluid from the body. The stages are numbered from 1 to 5 based on kidney function:

  • Stage 1 indicates that kidney function is only slightly affected.
  • Stage 5 signifies severe impairment of kidney function.

Doctors assess the stages of kidney disease by measuring the glomerular filtration rate (GFR). This calculation takes into consideration the level of creatinine in the blood, as well as factors such as your age, race, and gender.

Briefly stated

Stage-1 Renal Impairment ­ Minor Renal Injury Filtration volume: 90ml/mt or more

Stage-2 Renal Impairment ­ A slightly lower filtration rate: 60ml to 90ml/mt90ml/mt

Stage-3 Renal Impairment - Very Low Filtration rate: 30 ml to 59ml/mt59ml/mt

Stage-4 Renal Impairment - Very Low Filtration Rate: 15 ml to 29ml/mt29ml/mt

Stage-5 Renal Impairment ­ Very Low Filtration Rate: 15 ml to 29 ml/mt and more.

3.6 What level of creatinine indicates renal failure?

Blood creatinine levels above 1.2 mg in women and 1.4 mg in men may be a sign that the kidneys are not functioning properly. As this kidney disease progresses, the amount of creatine in the blood gradually increases.

Types of Kidney Diseases — Video Guide
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Chapter 4

Chapter 4

Acute Kidney Failure (AKI) — Causes, Symptoms & Treatment

4.1. Acute Sudden Renal Failure (Acute Kidney Injury)

Acute Kidney Injury (AKI) occurs when the kidneys suddenly lose their ability to function well. This can happen quickly, within hours or over a couple of days. The good news is that AKI is often reversible. If treated promptly and properly, many people can regain normal kidney function, especially if there are no other health problems.

4.2. Causes of Acute Kidney Injury:

Problems with Blood Flow to the Kidneys:

  • Infections
  • Low blood volume or reduced blood flow to the kidneys
  • Medicines that widen blood vessels, like some pain relievers
  • Medications that lower blood pressure
  • Severe burns can cause the body to lose a lot of fluids.
  • Heart failure
  • Liver failure

Obstruction of urine flow from the kidneys can occur due to:

  • Kidney stones, which are hard deposits that block urine flow.
  • Swelling from a prostate tumor in men can interfere with urine flow.
  • Cancers of the bladder, cervix, colon, or prostate that may block the urinary tract.
  • Blood clots in the urinary system can prevent urine from passing.
  • Damage to the nerves that control the bladder can affect how urine is released.

Direct impacts on the kidneys can result from:

  • Over-the-counter pain relievers (like NSAIDs), some cancer treatments, or antibiotics that can harm kidney tissue.
  • Infections of the ureters or autoimmune diseases (like uveitis or vasculitis) can affect kidney function.
  • Blockages in the kidney's tiny filtering tubes caused by fat (cholesterol) or bloodrelated substances.
  • Hemolysis (the breakdown of red blood cells) that can happen after blood transfusions or from muscle injury, releasing harmful substances.
  • Certain bites from snakes or small insects can directly damage the kidneys.

4.3 Risk Factors for Acute Kidney Failure:

Acute kidney failure can happen suddenly, and some factors can increase your risk, especially if you have other health problems. Here are some common risk factors:

  1. Staying in the Hospital for a Long Time: If you're hospitalized for an extended period, particularly in an intensive care unit (ICU), your chances of developing kidney issues rise.
  1. Existing Health Conditions:

o Diabetes: If you have diabetes, it can gradually harm your kidneys.

o Older Age: The older you are, the more likely you are to experience kidney problems.

o Heart Disease: If you have coronary heart disease, it can affect blood flow to your kidneys.

o High Blood Pressure or Heart Failure: These conditions can put extra stress on your kidneys and increase the risk of damage.

  1. Chronic Kidney or Liver Problems: If you've had ongoing issues with your kidneys or liver, you are at a higher risk of suddenly experiencing kidney failure.

4.4 What are the symptoms of acute renal failure (AKD)?

Urinating less than normal
Swelling in the feet, especially the ankles
Feeling very tired
Shortness of breath
Itching on the body
Loss of appetite
Nausea or vomiting
Confusion in the mind
Pressure or pain in the chest
Muscle cramps
Seizures or loss of consciousness (coma)
Abdominal or back pain

4.5 What Tests Should Be Done to Diagnose Acute Renal Failure?

  1. Initial Assessment: Your doctor will start by asking you about your symptoms and how long you've been experiencing them.
  1. Physical Examination: They will conduct a physical exam to check for any signs of kidney problems.
  1. Laboratory Tests: Your doctor will order some tests, including blood tests, urine tests, and imaging tests, to get a complete picture of your kidney health.

Blood Tests:

o Creatinine: This is a waste product that comes from muscle activity.Usually, your kidneys remove creatinine from your blood. If your kidneys aren't working well, creatinine levels will rise.

o Urea: Another waste product that your kidneys normally filter out. When kidney function decreases, urea levels in the blood also increase.

o Potassium: This is an essential nutrient for your body. If your kidneys are not functioning properly, potassium levels can become too high. In certain rare kidney diseases, they may even drop.

Sodium Levels:

  • Sodium is an essential nutrient that helps maintain balance in your body. If sodium levels are off, it usually indicates that your kidneys may not be functioning properly.

Urine Tests:

  • Your doctor will mainly check your urine for sugar and protein, as well as for iron and minerals. They will also look for the presence of blood cells or clots in the urine. The results from these tests help to identify any issues that may be affecting your kidney function.

Kidney Biopsy:

  • If the previous tests don't provide clear answers, your doctor may recommend a kidney biopsy. This involves using a thin needle to take a small sample from your kidney, which is then examined under a microscope. This test is not for everyone; it is used when the cause of kidney problems is unclear.

Imaging Tests:

  • Imaging tests like ultrasound or CT scans can show if the kidneys are enlarged or if there are any blockages in the urinary tract. These tests help identify not only kidney stones but also any issues with the blood vessels connected to the kidneys.

4.6 Tests and Treatment Methods for Acute Kidney Injury

  1. Imaging Tests:

o Tests like MRI can help understand the condition of the renal tubules, which are important parts of your kidneys.

  1. Injection Methods for Acute Kidney Injury:

o Sometimes, if a person experiences severe acute kidney injury, they may need to be hospitalized for intensive care. If there aren't any major complications, the kidneys often have a good chance of healing with appropriate medical treatment.

o Early diagnosis of acute kidney injury is crucial. It significantly increases the likelihood of recovery when proper interventions are carried out. These interventions may include:

Changing your diet

Taking necessary medications

Receiving intravenous (IV) fluids

Removing any blockages affecting the kidneys

Undergoing dialysis if needed

  1. Dietary Restrictions:

o While your kidneys are healing, your doctor will likely recommend limiting your intake of salt and potassium. This is important because both of these substances are usually removed from our bodies by the kidneys.

o While simply changing your diet cannot fix acute kidney injury, it can help manage related conditions like heart failure or dehydration.

o If you need to reduce potassium in your diet, avoid foods like bananas, oranges, rice varieties, gooseberries, and excessive tomatoes, as these are high in potassium. Instead, include fruits like apples and guavas which are lower in potassium.

Medicines: When the kidneys aren't working well, levels of phosphorus and potassium can get too high in the body. To help lower these levels, doctors may prescribe laxatives. This helps prevent some of the problems that can arise from kidney failure.

Dialysis Complications: If your kidneys are struggling a lot, you might need dialysis until they start to heal. Hemodialysis is the type of blood purification treatment that is commonly used today. It doesn't fix kidney failure, but it acts like the kidneys while they recover. This process can help the kidneys heal themselves over time. If the kidneys don't recover during a tough time, you might need to rely on dialysis for the long term.

4.7 How to Prevent Acute Kidney Failure?

To lower the risk of sudden kidney failure, it's important to adopt healthy habits. One thing to avoid is buying medications from pharmacies without asking a doctor first, especially over-the-counter pain relievers (OTC). Using pain relievers like aspirin, ibuprofen, naproxen, and acetaminophen too much or for a long time can be harmful to your kidneys.

Even if you have a low urinary tract infection, it's important to stay cautious. Other health issues can lead to kidney cysts and may cause kidney problems, even if you feel fine. So, it's crucial to be careful and pay attention to your health.

Always follow your doctor's advice closely.

Healthy Lifestyle Tips:

  • Maintaining a healthy lifestyle is very beneficial. Regular exercise, a good diet, and keeping a healthy weight can help protect your kidneys.

4.8 How to Prevent Complications?

  • If you are overweight, work on losing some weight.
  • Stay active; regular physical activity can help keep your blood sugar levels in check.
  • If you smoke, make an effort to quit.
  • Get a medical check-up at least once a year to assess the health of your kidneys.
  • Take your prescribed medications regularly and as directed by your doctor.
  • Blood Pressure: Keep your blood pressure below 140/90. Talk to your doctor to find the best level for you.
  • Blood Sugar: If you have diabetes, try to keep your blood sugar within a healthy range.
  • Cholesterol: Maintain healthy levels of fat (cholesterol) in your blood.
  • Salt Intake: Use less salt when cooking or eating.
  • Healthy Diet: Eat more fruits and vegetables.

4.9 Can Acute Kidney Failure Be Treated?

Yes, in most cases, sudden kidney failure can be treated, and people recover. However, some may develop long-term kidney problems (chronic kidney disease). If serious infections in the urinary tract persist, it can lead to harmful waste build-up, and excess salt and water in the body. In such cases, ongoing treatments like dialysis may be needed.

Acute Kidney Injury (AKI) — Video Guide
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Chapter 5

Chapter 5

Chronic Kidney Disease (CKD) — Causes, Symptoms & Prevention

5.1 What is Chronic Kidney Disease (CKD)?

  • Chronic kidney disease (CKD), also known as chronic kidney failure, happens when your kidneys slowly lose their ability to work properly over time.
  • Normally, your kidneys help remove waste and extra nutrients from your body through urine.
  • When your kidneys stop working well, harmful waste and nutrients start to build up in your body, which can make you sick.

5.2 What Causes Chronic Kidney Disease?

The main causes of CKD are:

  1. Diabetes: High blood sugar levels can damage your kidneys.
  2. High Blood Pressure: This puts extra strain on your kidneys and can lead to damage

over time. When you visit your doctor:

  • They will ask about your medical history to find out what might be causing your kidney problems.
  • They might suggest stress tests or other tests to check how well your kidneys are working.
  • The doctor may also ask about your family's health to see if kidney issues run in the family.
Diabetes
High blood pressure
Medicines that affect the kidneys
Polycystic kidney disease
Genetic disorders
Kidney damage from infections or abscess
Long-term blockages in the urinary tract

5.3 What Are the Symptoms of Chronic Kidney Disease (CKD)? What Should You Watch

For? In the early stages, CKD often has no noticeable symptoms. But as the kidney damage worsens, you might experience:

  1. Urinary Changes: o Needing to urinate more often. o Seeing blood or foam in your urine.
  1. Swelling: o Puffiness around your eyes. o Swollen hands, feet, or ankles.
  1. Other Symptoms: o Feeling nauseous or vomiting. o Difficulty concentrating or staying focused. o Always feeling tired, weak, or powerless. o Trouble breathing or shortness of breath. o Muscle cramps. o Dry and itchy skin. o Darkened skin tone. o Numbness or tingling in your hands or feet.

o High blood pressure.

5.4 What Are the Complications of Chronic Kidney Disease?

If CKD is not treated, it can lead to several other health problems, such as:

  1. High Blood Pressure
  2. Diabetes
  3. Heart Disease
  4. Being Overweight
  5. Anemia
  6. Fluid Retention
  7. Mineral supplements
  8. Acidity changes
  9. Arthritis

5.5 When Should a Patient with Chronic Kidney Disease See a Doctor?

If you have chronic kidney disease and experience any of the following symptoms, contact your doctor immediately:

  • Shortness of breath or trouble breathing.
  • Chest pain.
  • Swelling in your ankles or feet.
  • Sudden weight gain (more than 3 kilos in a few days).
  • Little or no urine.
  • Blood in your urine.
  • Nausea or vomiting.
  • Stomach pain.
  • Difficulty speaking or slurred speech.
  • Dizziness or fainting.
  • Seizures or convulsions.

5.6 Why Is Medical Treatment Necessary for Chronic Kidney Disease?

There is no permanent cure for chronic kidney disease, but early treatment can slow its progression. For severe cases, treatments like dialysis or a kidney transplant may become necessary. Starting medical care early helps delay the need for dialysis or transplants and reduces complications.

5.7 What are the treatment options for different stages of chronic kidney disease?

Chronic kidney disease (CKD) is usually managed through lifestyle changes and medical care.

  • Early stages: The main goal is to slow the disease and protect the kidneys. This can involve eating healthier, exercising, controlling blood pressure and sugar levels, and taking medications as needed.
  • Worsening disease: As CKD progresses, the focus remains on managing blood pressure and blood sugar while using medicines that help protect the kidneys.
  • Severe stages: If kidney function becomes very poor, treatments like dialysis (a machine that helps clean your blood) or a kidney transplant may be necessary.
  • End-stage kidney disease: Dialysis or a kidney transplant is usually essential to stay healthy.

Always work with your doctor and healthcare team to decide the treatment plan that suits you best.

5.8 What is the goal of blood pressure control in chronic kidney disease?

Keeping your blood pressure at or below 130/80 is key for people with CKD. This target has been shown to lower the chances of further kidney damage and even reduce the risk of death in the long term.

5.9 Should I change my diet? Do I need to see a dietitian?

Yes, diet plays a big role in managing CKD. Eating the right foods can help protect your kidneys and prevent complications. You might need to:

  • Limit salt and sodium to help control blood pressure.
  • Watch your protein intake so your kidneys don't have to work as hard.
  • Keep an eye on potassium and phosphorus levels, depending on your condition.

Yes, it's very important to follow the advice of a qualified dietitian if you have chronic kidney disease (CKD). A dietitian will help create a meal plan tailored to your condition. This plan will:

  • Focus on meeting your nutritional needs.
  • Recommend what foods to eat or avoid based on the extent of kidney damage.

By following their advice, you can help protect your kidneys and improve your overall health.

5.10 Can other health problems affect chronic kidney disease?

Yes, other health conditions can increase the risk of kidney damage or worsen CKD. For example: High blood pressure, Uncontrolled diabetes, Heart disease, Liver disease. These can strain your kidneys and lead to further damage.

Chronic Kidney Disease (CKD) — Video Guide
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🩺 Need Expert Nephrology Care in Salem?

Consult senior nephrologists Dr. Jones Ronald & Dr. Hari Janakiraman for chronic kidney disease evaluation & treatment.

Nephrology Dept →Book Appointment
Chapter 6

Chapter 6

Chronic Kidney Disease Treatment

6.1 What are the treatment options for people with CKD stages 1 to 5?

There is no complete cure for chronic kidney disease (CKD), but treatments can help manage symptoms and slow down kidney damage. These treatments aim to protect your kidneys and overall health. They include:

  • Blood pressure medications:
  • Cholesterol-lowering drugs:
  • Diabetes medications:
  • Dialysis: A treatment that uses a machine to clean your blood when your kidneys can't.
  • Kidney transplant: Surgery to replace the damaged kidney with a healthy one from a donor.

Regular exercise and a healthy lifestyle can also improve your symptoms and help prevent CKD from getting worse.

6.2 How long can someone with kidney failure live without dialysis?

When the kidneys completely fail, dialysis is often necessary to survive. However, without dialysis, people with kidney failure may live for only a few days to a few weeks, depending on their overall health and kidney function.

6.3 Can kidney failure be treated without dialysis?

Dialysis is often a life-saving treatment for people with kidney failure, but it might not be the only option in some cases. Your doctor will assess your condition and may recommend other approaches if dialysis isn't suitable or necessary for you.

Here's what you should consider:

  • Discuss with your family:
  • Talk to your doctor: Explore alternative treatments and understand your options.
  • Get support: Seek medical advice and, if needed, psychological counseling to cope with the situation.
  • Supportive care: Focus on treatments that help reduce symptoms and improve quality of life.

Hepatitis B Vaccination for Kidney Disease Patients

Yes, people with kidney disease should get the Hepatitis B vaccine before starting dialysis. Why? Because:

  • Chronic kidney disease weakens the immune system, making it harder to fight infections.
  • Vaccinating before dialysis helps the body build better immunity to the Hepatitis B virus.

It's strongly recommended to get vaccinated early to protect yourself effectively.

  • Why is the Hepatitis B vaccine important for dialysis patients?

Patients on dialysis have a higher risk of getting infected with the Hepatitis B virus because they undergo frequent blood tests, blood transfusions, and blood purification during dialysis. The vaccine helps protect them from this serious infection, which is especially important for their overall health.

  • When and how should the Hepatitis B vaccine be given?

The Hepatitis B vaccine is given in a series of three doses to provide effective protection. The first dose is the initial injection, followed by the second dose one month later. The third dose is administered six months after the first dose, completing the vaccination schedule. In some cases, patients on dialysis may need booster doses at regular intervals to maintain immunity.

  • What is an AV Fistula?

An AV (arteriovenous) fistula is a surgical connection between an artery and a vein, usually in the arm. It helps prepare your blood vessels for dialysis by strengthening them to handle the process of filtering blood.

  • How is an AV Fistula created?
  • For most right-handed people, the fistula is made in the left arm, either near the wrist or elbow.
  • During the procedure, a surgeon uses local anesthesia to numb the area before connecting the artery to the vein.
  • Over time, the fistula becomes thicker and stronger, making it easier to use for dialysis.
  • When should an AV Fistula be created?

If your doctor thinks you might need dialysis in the future, they may recommend creating an AV fistula early. This is because it takes about 2­3 months for the fistula to heal and become strong enough to use for dialysis. Starting the process early ensures it's ready when needed.

  • Are there any precautions to follow?

Yes, if you have kidney problems and are preparing for dialysis, avoid having blood drawn or injections given in the arm where the fistula will be created (usually the left arm for right-handed people). This helps keep the blood vessels in that arm healthy and intact. A well-functioning fistula ensures smooth and uninterrupted dialysis for a long time.

Chronic Kidney Disease Treatment — Video Guide
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Chapter 7

Chapter 7

Myths about Kidney Disease — Explanations

Myth: Kidney disease is very rare. Fact: Kidney disease is more common than you might think. Around 17 out of every 100 Indians have some form of kidney disease. In the last 15 years, the number of deaths from kidney-related conditions in India has doubled.

Myth: There's nothing you can do to prevent kidney disease. Fact: Most cases of kidney disease can be prevented. About 75% of kidney failure cases are caused by diabetes and high blood pressure. By managing these conditions through proper treatment, a healthy lifestyle, and regular check-ups, you can significantly lower your risk of kidney disease.

Myth: You'll know if you have kidney disease. Fact: Kidney disease often shows no symptoms until it's in the late stages. It progresses very slowly over time, and 96% of people with early-stage kidney disease are unaware they have it. Regular blood and urine tests are essential for early diagnosis and treatment.

Myth: Kidney stones can lead to kidney damage. Fact: Kidney stones rarely cause permanent kidney damage. About 1 in 10 people develop kidney stones, but for most, they don't cause long-term issues. Kidney stones are often painful, which prompts treatment. Drinking plenty of water every day can help prevent kidney stones to some extent.

Myth: No one knows what causes kidney disease. Fact: The two main causes of kidney disease are diabetes and high blood pressure. These conditions damage the small blood vessels in the kidneys, leading to kidney problems. While there are other risk factors, managing these two conditions significantly reduces the risk of kidney disease.

Myth: I'm healthy, so I don't have kidney problems. Fact: Chronic kidney disease (CKD) often has no early symptoms, which means you may not realize you have it until it's more advanced. Regular tests are essential to check your kidney health. Your doctor can recommend the right tests to assess kidney function and provide guidance if anything is wrong. Myth: Drinking lots of water keeps your kidneys healthy. Fact: Staying hydrated is important and can help prevent kidney stones and some urinary tract infections. However, drinking water alone cannot completely protect you from kidney disease or infections. Always consult a medical professional for personalized advice on keeping your kidneys healthy.

Myth: Renal failure occurs if one kidney fails or is removed. Fact: Renal failure happens only when both kidneys fail. If one kidney fails completely or is removed, the other kidney can usually function well enough to keep the body healthy. In such cases, blood tests often show normal levels of urea and creatinine. Renal failure occurs only when both kidneys stop working, leading to a buildup of waste products in the body, which can be detected through blood tests showing high urea and creatinine levels.

Myth: Swelling in the legs always indicates kidney failure. Fact: Swelling in the legs can occur in kidney diseases but doesn't always mean kidney failure. Conditions like nephrotic syndrome, heart problems, liver disease, or issues with fluid movement in the body can also cause swelling. In these cases, kidney function may still be normal. Swelling alone is not a definitive sign of kidney failure.

Myth: All patients with kidney failure experience nausea. Fact: Not everyone with kidney failure experiences nausea or vomiting. While many patients do feel unwell as kidney function declines, others may not show these symptoms, even in advanced stages. Similarly, a lack of nausea doesn't mean the kidneys are functioning properly, so regular check-ups are crucial.

Myth: All kidney disease patients should drink a lot of water. Fact: This isn't true for everyone. For patients with reduced kidney function and low urine output, drinking too much water can worsen the problem. They need to control their water intake to avoid fluid overload. However, people with kidney stones or urinary tract infections (without significant kidney damage) are advised to drink plenty of water to help flush out infections and prevent stone formation. Always follow your doctor's advice regarding water intake based on your specific condition. Myth: My blood creatinine level is slightly higher than normal, but I feel fine, so there's nothing to worry about. Fact: A slight increase in creatinine can be an early sign of kidney problems and should not be ignored. Many kidney diseases can cause damage without showing obvious symptoms. It's important to consult a urologist or nephrologist as soon as possible to identify the cause and take appropriate action.

Myth: Dialysis cures kidney failure. Fact: Dialysis does not cure kidney failure. It is a treatment that helps replace some of the functions of the kidneys, like removing waste, extra fluid, and balancing electrolytes and acid levels in the body. While dialysis is life-saving and essential for people with kidney failure, it doesn't restore kidney function. Instead, it does the work that failing kidneys can no longer do, helping patients stay alive and manage their condition.

Myth: Men and women cannot donate kidneys to the opposite sex during a transplant. Fact: This is not true. Men and women can donate kidneys to each other. The structure and function of kidneys are the same in both sexes, and gender does not affect the success of the transplant. What matters is compatibility between the donor and recipient, not their gender.

Myth: I feel fine, so I don't think I have a kidney problem. Fact: This is not true. Chronic kidney disease (CKD) often shows no symptoms in its early stages. Many people don't realize they have kidney problems until the disease progresses significantly. If you have risk factors such as diabetes, high blood pressure, or a family history of kidney disease, it's important to get regular check-ups, including a urinalysis, even if you feel healthy. Early detection can prevent the need for dialysis or other advanced treatments later.

Myth: I urinate a lot, so my kidneys must be working well. Fact: Frequent urination doesn't always mean your kidneys are healthy. In the early stages of kidney disease, the kidneys may lose their ability to concentrate urine, causing excessive urination, especially at night. This could be an early sign of kidney damage and should not be ignored.

Understanding the Importance of Creatinine Levels: Even a slight increase in blood creatinine can indicate kidney damage. Creatinine is a waste product filtered by the kidneys, and its levels in the blood reflect how well the kidneys are functioning. For example:

  • A blood creatinine level of 2.6 mg/dL suggests that kidney function has already decreased by more than 50%. At this stage, early detection and proper treatment can help preserve the remaining kidney function.
  • When creatinine levels exceed 5.0 mg/dL, it means the kidneys have lost approximately 80% of their function, and the patient is likely in the advanced stages of kidney failure.

When kidney function is severely impaired, creatinine levels in the blood become significantly elevated. For example:

  • A creatinine level above 10 mg/dL indicates that 90% of kidney function has already been lost, marking the transition to end-stage kidney disease (ESKD).
  • At this stage, the kidneys can no longer filter waste or maintain the body's chemical balance, leaving limited options such as dialysis or a kidney transplant. Unfortunately, medical treatments alone are no longer effective in reversing the condition.

Preserving Remaining Kidney Function: While some residual kidney function can be maintained with proper care, it's important to understand that ESKD requires life-saving interventions like dialysis or transplantation. Delaying treatment can result in severe complications.

Myth: Patients with kidney failure who start dialysis must continue it permanently. Fact: This is not always true. Whether dialysis is permanent or temporary depends on the type of kidney problem:

  • Acute Kidney Injury (AKI): This is a sudden loss of kidney function, often caused by infections, dehydration, or certain medications. AKI is usually reversible, and dialysis may only be needed for a short time until the kidneys recover.
  • Chronic Kidney Disease (CKD): In advanced stages, dialysis becomes a permanent requirement to replace kidney function.

It's important not to delay dialysis out of fear that it will be permanent. For those with AKI, timely dialysis can support the kidneys and give them a chance to recover fully.

Chronic kidney disease is a chronically worsening and irreversible kidney failure. This stage of kidney disease (end stage kidney disease) is common

Lifelong dialysis support or kidney transplant surgery is required.

Myth: Male kidneys are located in a pouch between the legs. Fact: This is not true. Both men and women have their kidneys located at the back of the abdomen, on either side of the spine. They are small, bean-shaped organs that filter blood and produce urine. In men, the testicles are located in a pouch called the scrotum between the legs, but the kidneys are situated higher up in the body, not in the groin area. Myth: Now that my blood pressure is normal, I no longer need to take my blood pressure medications. If I stop taking them, I feel better. Fact: Stopping blood pressure medications without your doctor's advice can be very dangerous. High blood pressure often has no symptoms, which is why it's called a "silent killer." If left untreated, it can lead to serious health problems like heart attacks, kidney failure, and strokes. Even if you feel fine, it's important to keep taking your prescribed medications to protect your vital organs and maintain your overall health. Always follow your doctor's instructions regarding your blood pressure treatment.

Myth: Once you start dialysis, you need to do it for the rest of your life. Fact: This isn't always the case. Dialysis is a treatment that helps perform the functions of the kidneys when they fail. In cases of acute kidney failure, which happens suddenly, dialysis may only be needed temporarily until the kidneys recover. However, for those with chronic kidney disease in its advanced stages, dialysis may be necessary on a long-term basis unless they receive a kidney transplant. It's important to discuss your specific situation with your doctor to understand the best treatment plan for you.

Myth: Kidney transplant cures kidney failure. Fact: A kidney transplant is a life-saving treatment for those with end-stage kidney failure, but it doesn't completely cure kidney disease. Even after a transplant, patients need to take medications and follow medical advice to prevent complications and protect the new kidney. Kidney failure cannot be entirely reversed, but transplantation can greatly improve quality of life.

Myth: Only people with diabetes or high blood pressure get kidney disease. Fact: While diabetes and high blood pressure are major risk factors for kidney disease, anyone can develop it. Other causes include bacterial infections, family history of kidney disease, chronic urinary tract blockages, excessive use of painkillers, aging, genetics, and environmental factors. It's essential to be aware of these risks to protect your kidneys.

Myth: Having kidney failure only means you have kidney disease. Fact: Kidney disease progresses through different stages, from mild to severe, and kidney failure is the final stage. Early stages often have no symptoms, so regular tests and medical check-ups are crucial for early detection and treatment. Identifying kidney disease early can help prevent it from progressing to kidney failure. Myth: Dialysis is the only treatment for kidney disease. Fact: Dialysis is one treatment option for kidney failure, but it's not the only one. Other treatments, like medications, kidney transplant surgery, and lifestyle changes, can also manage kidney disease effectively. The best treatment depends on the stage of the disease and the patient's specific condition.

Myth: Only old people get kidney disease. Fact: Kidney disease can affect people of all ages. However, the risk does increase with age. Other common causes include diabetes, high blood pressure, and a family history of kidney disease.

Myth: If you have kidney disease, you will have symptoms. Fact: In the early stages of kidney disease, most people don't notice any symptoms. That's why regular health check-ups and medical advice are crucial for detecting the disease early, even before symptoms appear.

Myth: Kidney disease is not serious. Fact: Kidney disease can become a serious condition if left untreated. The kidneys are essential for removing waste from the body. When they don't work properly, harmful waste builds up in the blood, increasing the risk of severe health problems.

Myth: There is no cure for kidney disease. Fact: While kidney disease cannot always be cured, it can be managed effectively. Treatments such as medications, a healthy diet, dialysis, and kidney transplants can help control the disease and prevent it from worsening.

Myth: Kidney disease cannot be prevented. Fact: You can take steps to lower your risk of kidney disease. Maintaining healthy blood pressure, controlling diabetes, avoiding smoking and alcohol, and eating a balanced diet are effective ways to protect your kidneys.

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Chapter 8

Chapter 8

Dialysis & Types of Dialysis

8.1 What is dialysis?

Dialysis is a treatment for people whose kidneys have stopped working properly. When your kidneys fail, they can't effectively filter waste and toxins from your blood, causing harmful substances to build up in your body. Dialysis steps in to do the work of your kidneys by removing waste, toxins, and excess fluid from your blood, helping to keep your body balanced.

8.2 What are the types of dialysis?

There are two main types of dialysis:

  1. Hemodialysis (Blood Purification):
  1. Peritoneal Dialysis
  1. Peritoneal Dialysis

In peritoneal dialysis, a special fluid is introduced into your abdominal cavity through a soft tube. The fluid absorbs waste products and excess fluid from your body, using the lining of your abdomen (peritoneum) as a natural filter. After a few hours, the used fluid is drained and replaced with fresh fluid. This process can often be done at home, allowing more flexibility in daily life.

8.3 Does dialysis cure chronic kidney disease?

No, dialysis does not cure chronic kidney disease. It only performs some functions of a healthy kidney, such as removing waste and excess fluid. If a kidney transplant isn't an option for you, dialysis might be a lifelong necessity to help manage your condition.

8.4 What is Hemodialysis (Blood Purification)?

Hemodialysis is a procedure where a machine draws your blood, cleans it using a filter called a dialyzer (artificial kidney), and returns the purified blood to your body.

  • Standard Hemodialysis: Typically done in a hospital or dialysis center, each session lasts 4­5 hours and is performed three times a week.
  • Home Hemodialysis: With proper training, you can perform shorter sessions at home, 4­7 days a week. For added convenience, you can opt for overnight hemodialysis while you sleep, giving you more freedom during the day.

8.5 How is Hemodialysis (Blood Purification) Performed?

Hemodialysis involves removing a small amount of your blood, filtering it through a special machine called a dialyzer (artificial kidney), and returning the cleaned blood to your body. This process removes waste, extra fluid, and toxins.

The machine also monitors your blood temperature, checks for air bubbles, and ensures sodium and potassium levels are balanced during the process.

Each session usually lasts 4 to 5 hours and is typically done three times a week in a hospital or dialysis centre. If you prefer, you can also perform hemodialysis at home. Ideally, 15 hours of dialysis per week is recommended, which can mean 4­5 hours a day, three days a week.

8.6 What Happens During Hemodialysis?

During hemodialysis, the machine performs several critical functions:

  • Blood is drawn through a needle inserted in your arm.
  • Inside the dialyzer, the blood flows through a filter where waste and toxins are removed.
  • These wastes are passed into a special dialysis solution, which contains carefully balanced amounts of water, salt, and other additives to ensure the process is safe and effective.
  • After filtering the blood, the purified blood is returned to your body through another needle inserted in your arm.
  • The machine regulates the speed at which blood flows in and out of your body, monitors your blood pressure, and adjusts for any heat changes to ensure comfort and safety.

8.7 Is Hemodialysis Painful? What Can a Patient Do During the Session?

When starting hemodialysis, needles are inserted into the fistula or graft in your arm, which may cause mild pain. However, most patients do not experience significant discomfort during the procedure. Dialysis itself is usually painless, but some patients may occasionally experience side effects like nausea, vomiting, headaches, or muscle cramps. These issues can often be avoided by carefully following dietary restrictions, particularly with salt and fluid intake.

During the dialysis session, you can engage in various activities to pass the time:

  • Read books or magazines.
  • Watch TV or listen to the news.
  • Use a laptop or tablet for work or entertainment.
  • Enjoy coffee or tea if permitted.

8.8 What Are the Common Complications During Dialysis?

Some patients may experience the following complications:

  • Low blood pressure
  • Nausea and vomiting
  • Headaches
  • Muscle cramps
  • Infection
  • Fever, chills, and shivering
  • Dizziness
  • Blood clotting
  • Low blood sugar
  • Body itching and dryness

8.9 What Are the Benefits and Challenges of Hemodialysis?

Benefits of Hemodialysis:

  • When an arteriovenous (AV) fistula is used for accessing the bloodstream, the chances of complications are significantly reduced.
  • AV fistulas are durable and often last for many years, requiring fewer surgical interventions compared to other methods like catheters.
  • Hemodialysis is typically done three times a week in a dialysis center, allowing patients weekends off (e.g., Sundays) for rest while the machines are cleaned.
  • Dialysis sessions at centers are monitored by trained healthcare staff who ensure your health is stable and vaccinations are up to date.
  • Dialysis centers provide opportunities for patients to interact and connect with others undergoing similar treatments, fostering a sense of community.
  • Patients can use the dialysis session for relaxation or engaging in light activities like reading or watching TV. In fact, exercising lightly during dialysis is now considered beneficial for health.
  • Compared to other forms of treatment, the risk of infection is relatively lower in hemodialysis, especially when proper precautions are followed.
  • Hemodialysis can also be performed at home, giving patients the flexibility to manage their treatment schedule according to their lifestyle.

Challenges of Hemodialysis

If Done at a Clinic:

  1. Time Commitment:

o Each session lasts 4­5 hours, and you need to visit the clinic three times a week, which can be time-consuming.

  1. Strict Schedule:

o Hemodialysis requires sticking to a fixed schedule, making it challenging to adjust for other commitments.

  1. Travel Hassles:

o Traveling to the dialysis center can be inconvenient, especially in busy traffic or long distances. Planning in advance is essential.

  1. Diet and Fluid Restrictions:

o Patients must follow strict dietary guidelines and limit fluid intake to prevent complications.

  1. Appearance of AV Fistula:

o The AV fistula used for dialysis may appear as a swollen or noticeable bump on the arm, which some may find unattractive.

If Done at Home:

  1. Need for Assistance:

o A trained dialysis assistant is required to help with the procedure and provide medical support.

  1. Setting Up the Environment:

o Proper arrangements are necessary, including a clean space, reliable electricity, clean water, and proper plumbing.

Potential Side Effects:

  • Low blood pressure
  • Shortness of breath
  • Nausea

8.10 What Is Peritoneal Dialysis?

Peritoneal dialysis, also known as abdominal dialysis, uses the lining of your abdomen (called the peritoneum) to filter your blood. Here's how it works:

A special solution, called dialysis fluid, is introduced into your abdominal cavity through a small tube.The blood vessels in the abdominal lining act as natural filters, removing waste, toxins, and excess fluid from your blood into the dialysis fluid.

8.11 What Are the Types of Peritoneal Dialysis?

There are two main methods of performing peritoneal dialysis at home:

  1. Automated Peritoneal Dialysis (APD):

o This method uses a machine called a cycler, which performs dialysis while you sleep.

o Continuous Ambulatory Peritoneal Dialysis (CAPD). This is a manual method where you fill and drain the dialysis solution yourself.

8.12 What Dietary Changes Are Recommended for Patients on Peritoneal Dialysis (CAPD)?

Following the right diet is crucial for staying healthy during peritoneal dialysis (CAPD). Here are some key recommendations:

  1. Protein Intake:

o Aim: Consume about 1 gram of protein per kilogram of body weight per day.

o Why: This helps maintain muscle mass and prevents malnutrition, which is common in dialysis patients.

  1. Sodium (Salt) Limit:

o Aim: Restrict sodium intake to 2­3 grams per day.

o Why: Too much salt can cause fluid retention, swelling, and high blood pressure, which are harmful to kidney patients.

  1. Balanced Potassium Levels:

Importance: Proper potassium levels are necessary to avoid muscle cramps and heartrelated issues.It can be harmful to people suffering from kidney disease.

Limit Potassium-Rich Foods. Avoid or reduce foods like bananas, oranges, carrots, and gooseberries if your potassium levels are high. High potassium can cause dangerous heart rhythm problems in people with kidney disease.

opt for Complex Carbohydrates. Include foods like whole grains, fruits, and vegetables in your diet. These are rich in nutrients and help stabilize blood sugar levels. Fluid Intake: Drink enough water to help flush out waste, but consult your doctor to determine the right amount for your condition. You can also include drinks like low-fat milk, depending on your dietary plan.

Personalized Meal Plans. Work with a healthcare team, including a dietitian, to develop a diet tailored to your specific needs. A well-balanced and individualized diet helps manage your condition effectively.

8.13 How Long Can a Chronic Kidney Disease Patient Survive Without Dialysis?

The survival time for a person with chronic kidney disease who isn't on dialysis depends on several factors:

If the kidneys are still working a bit, waste removal may be slow, but it helps prolong survival. General health, other medical conditions, and how well dietary restrictions are followed play a big role. A strict diet and proper fluid control can help reduce the burden on the kidneys.

Signs that you may need dialysis include:

  • Vomiting and hiccups.
  • Fluid buildup in the body.
  • Shortness of breath.
  • Dry and itchy skin.
  • Loss of appetite and nausea.
  • Odor in the breath.
  • Decreased urine output.
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Chapter 9

Chapter 9

Kidney Transplant Surgery

9.1 What is a kidney transplant?

A kidney transplant is a surgical procedure where a healthy kidney from a donor is placed into a person whose kidneys are no longer working properly. The goal of this procedure is to restore kidney function and improve the recipient's overall quality of life. Kidney transplant surgery is usually performed when a person's kidneys permanently lose their ability to function and reach a stage called End Renal Disease(ERD), requiring dialysis or a kidney transplant.

9.2 When is a kidney transplant necessary?

A kidney transplant is typically recommended for individuals with end-stage kidney disease, where the kidneys can no longer function adequately. This may happen due to conditions like diabetes or high blood pressure. A transplant becomes essential when the kidneys are unable to filter waste and toxins from the blood effectively.

9.3 Why is a Kidney Transplant Performed?

Here are the reasons why a kidney transplant is performed:

  1. To improve quality of life: A kidney transplant is needed when various factors reduce quality of life, such as fatigue and difficulty breathing caused by kidney failure, along with the need for dialysis. The new kidney obtained through a transplant can alleviate these symptoms and significantly improve quality of life.
  1. To extend life expectancy: A kidney transplant helps extend the life expectancy of a person with kidney failure.
  1. To reduce the need for dialysis: Dialysis is a treatment that filters waste products and excess fluids from the blood when the kidneys are not functioning properly. It is not only time-consuming but can also be physically taxing. Therefore, a kidney transplant can reduce or even eliminate the need for dialysis.
  1. To improve overall health: A properly functioning transplanted kidney enhances overall health by effectively filtering waste products and excess fluids from the blood. It also helps reduce the risk of heart disease and high blood pressure.
  1. To reduce the burden of kidney failure on the body: Kidney failure can cause significant health problems. A kidney transplant helps reduce this burden by providing a new, functioning kidney.

9.4 What is the age limit for kidney transplant surgery?

There is no strict age limit for kidney transplants. The suitability of a transplant depends on several factors, such as the patient's overall health and the availability of a suitable kidney donor. Transplants generally have a higher success rate in younger patients, while older patients may face more challenges. Factors like overall health, existing medical conditions, and surgical risks are carefully evaluated to determine whether an elderly patient is a good candidate. Ultimately, the decision is made by the patient's medical team after considering all aspects of the individual's health and circumstances.

9.5 Who is eligible to donate a kidney?

A kidney donor must be a healthy individual who willingly agrees to donate one of their kidneys to someone in need.

  • Family connection: Donors are often close relatives of the recipient, such as a parent, sibling, or child, as they are more likely to match in blood and tissue types.
  • Age consideration: There is no strict age limit for donors, but younger donors typically experience fewer complications and have better transplant outcomes.
  • Good health: Donors must be in good overall health and free from conditions like diabetes or high blood pressure to ensure a safe surgery and recovery for both the donor and the recipient.

9.6 Who cannot donate a kidney?

Certain medical conditions make it unsafe for a person to donate a kidney. These include:

  • Uncontrolled high blood pressure
  • Uncontrolled diabetes
  • Cancer
  • HIV infection
  • Jaundice or infections like hepatitis
  • Severe mental health disorders that require treatment

9.7 What are the potential risks for a living kidney donor?

Kidney donation is generally a safe and effective surgical procedure, but like any surgery, it carries some risks. It is important for donors to be aware of potential complications, which include:

  • Pain after the surgery
  • Blood in the urine
  • Blood clots
  • Infections
  • Possible injury to nearby organs or blood vessels
  • Reactions to anesthesia
  • A small chance of developing chronic kidney disease in the future
  • Increased risk of high blood pressure

While serious complications are rare, most donors recover fully within a few weeks to a few months. Donors should carefully discuss these risks with their medical team before deciding to donate a kidney.

9.8 How is kidney transplant surgery performed?

A kidney transplant is a surgical procedure where a healthy kidney from a donor is placed into a recipient whose kidneys are no longer functioning properly. The patient's damaged kidneys are typically not removed. The new kidney can come from either a deceased donor (cadaver transplant) or a living donor. The healthy kidney is surgically connected to the recipient's blood vessels and bladder to restore normal kidney function.

Summary of Kidney Transplant Process and Complications

  1. Screening: The first step in a kidney transplant is being evaluated by a transplant committee. This team assesses your overall health, the severity of your kidney disease, and other medical conditions to ensure you are a suitable candidate for the procedure.
  1. Finding a Donor: Once approved for a transplant, the next step is finding a donor. This could be a living donor, such as a family member or friend, or a deceased donor who had previously consented to organ donation.
  1. Initial Tests: Before the surgery, you will undergo several medical tests to ensure your body is ready for the transplant. You will also start taking medications to suppress your immune system to prevent rejection of the new kidney.
  1. Surgery: The transplant surgery is performed under general anesthesia and typically lasts about 3 hours. The surgeon makes an incision in the lower right side of your abdomen to place the new kidney. The healthy kidney from the donor is carefully connected to your blood vessels and urinary system.
  1. Recovery: After the surgery, you'll stay in the hospital for a few days to recover. Medications will be provided to help your body accept the new kidney and prevent rejection. Close monitoring is crucial in the early stages. Over time, your blood creatinine levels will decrease as the new kidney starts functioning, but full recovery may take weeks or months.

Note: We hope this information was helpful. If you have any other questions about kidney transplant complications, please do not hesitate to contact us.

9.9 Can a Kidney Be Donated After Death?

Yes, kidneys can be donated after death, a process known as cadaver kidney transplantation. Kidneys from deceased donors are a precious, life-saving gift for patients waiting for a transplant. When a person passes away, their organs, including kidneys, can save or improve the lives of others.

To be a deceased donor, the donor must meet certain health criteria to ensure the kidney is safe for the recipient. If you wish to donate your kidneys after death, you can indicate your decision on your driver's license, state ID, or organ donor registry. It is equally important to discuss your decision with your family and loved ones, as they will play a crucial role in honouring your wishes.

9.10 What is Renal Rejection?

Renal rejection occurs when the recipient's immune system identifies the transplanted kidney as foreign and attacks it. The immune system's primary role is to protect the body by fighting off harmful invaders like bacteria and viruses. However, this natural defense mechanism can mistakenly target a newly transplanted kidney, leading to rejection. Managing rejection requires careful medical supervision, including medications to suppress the immune system and protect the transplanted organ.

His immune system will recognize this transplanted kidney as foreign and try to destroy it. This can lead to rejection of the new kidney. This can happen even if the kidney donor is a suitable close relative of the kidney recipient. Acute renal rejection is a serious side effect after renal transplantation. It can be life-threatening if not immediately noticed and treated accordingly. There are many safe medications available to prevent this.

9.11 Donation after kidney transplant complications. What medications should be taken to

prevent the patient from rejecting the transplanted kidney?

After a kidney transplant, it is important for the patient to take medications to prevent rejection of the transplanted organ. These medications, called immunosuppressants, help suppress the immune system from attacking the transplanted organ.

Some common immunosuppressive medications used after a successful kidney transplant include:

  • Prednisone
  • Mycophenolate Mopedil
  • Tacrolimus
  • Sarolimus
  • Cyclosporine
  • Azathioprine

It is very important for kidney transplant recipients to take these medications regularly as advised by their doctor. Because not doing so increases the risk of rejection of the transplanted kidney. Based on the type of transplant complication and the individual needs of the patient, these drugs are prescribed by the urologist.

9.12. Precautions to Follow After a Kidney Transplant:

  1. A kidney transplant is a major surgery, and its success depends on careful monitoring and adherence to specific guidelines. Here are important precautions to follow after the procedure:
  1. Take Medications Regularly: Always take the medicines prescribed by your doctor on time to prevent your immune system from rejecting the transplanted kidney.
  1. Maintain a Healthy Lifestyle: Eat a balanced diet, exercise regularly, and avoid smoking or drinking alcohol to ensure the transplanted kidney stays healthy.
  1. Follow Medical Advice: Keep in touch with your healthcare team through regular checkups to monitor your kidney's health and adjust your medications as needed.
  2. Protect Your Kidney: Avoid contact sports or activities that could result in injury to your abdomen, as they may harm the transplanted kidney.
  1. Stay Vaccinated: Get vaccinations for common infectious diseases like influenza and pneumonia to safeguard your health and the transplanted kidney.
  1. Stay Hydrated: Drink plenty of water to help flush out toxins and keep your transplanted kidney functioning efficiently.
  1. Avoid certain medications: Medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and herbal supplements, may interfere with the effectiveness of your medications. Also, it can also damage your liver. It is important to discuss any new medications or supplements you are taking with your transplant team.
  1. Avoid Contagious Situations. If you are taking immune-suppressing medications, you are more likely to develop yeast infections. So, it is better to avoid crowded places, events, public gatherings and poorly ventilated places.

9.13 What happens if a kidney transplant fails?

If a kidney transplant fails, it means that the transplanted kidney is not functioning properly, so the patient needs to undergo dialysis again or get another kidney transplant. There are many reasons why kidney transplants fail. These include rejection of the transplanted kidney by the immune system, infection in the recipient, or blockages in the blood vessels leading to the kidney.

When a kidney transplant fails, the patient usually has symptoms such as fatigue, weakness, and high blood pressure. As well as symptoms of kidney failure such as elevated blood levels, electrolyte imbalances and increased wastes in the blood. In some cases, the kidney received from a kidney transplant may need to be removed if it is not working properly, or if it causes complications.

9.14. What is Brain Death?

Brain death refers to the complete and permanent loss of all brain activity. In many countries, it is legally recognized as death. When someone is brain dead, their brain has suffered such severe damage that it can no longer function, even with the support of lifesaving machines. This condition is different from a coma, where a person may still have some brain activity and a chance of recovery. Brain death also differs from cardiac death, which happens when the heart stops beating.

9.15. Common Causes of Brain Death:

Brain death occurs when the brain stops functioning entirely and permanently. The most common causes include:

  1. Severe Head Injuries: These may result from road accidents, falls, or a strong blow to the head.
  1. Stroke: A stroke happens when blood flow to the brain is blocked or interrupted, causing brain cells to die.
  2. Brain Aneurysm: This occurs when a weak, bulging blood vessel in the brain bursts, leading to bleeding in the brain.
  1. Brain Tumors: Swelling or pressure caused by a tumor can damage brain function and lead to brain death.
  1. Severe Infections: Infections like meningitis or encephalitis can cause significant swelling in the brain, leading to irreversible damage.
  1. Cardiac Arrest: When the heart stops beating, the brain is deprived of oxygen. If this lack of oxygen continues for too long, brain death can occur.
  1. Drug Overdose: Certain drugs can damage the brain or disrupt its normal functioning, potentially leading to brain death.
  1. Drowning: When someone drowns, their brain may go without oxygen for an extended period, which can result in brain death.

9.16 Is Any Payment Made to the Family of a Kidney Donor?

In most countries, paying organ donors or their families is not allowed. The World Health Organization and governments worldwide have strict laws to ensure that organ donation is done voluntarily and without financial incentives. These regulations aim to prevent exploitation and maintain fairness in organ donation.

Organ donation is considered a noble and selfless act, done to help save the lives of others. However, for living donors, certain expenses like travel and accommodation may be covered to ease the process, but this should not be confused with payment.

9.17 Who Can Donate a Kidney Based on Blood Type?

Anyone can donate a kidney, but the donor's blood type must be compatible with the recipient's blood type or be of any other agreeable category. This is a crucial factor to ensure the success of the transplant.

Blood Type Compatibility Table:

Recipient's blood type Donor's blood type

O type O type

A type A or O type

B type B type or O type

AB type A, B, AB, or O type

This table highlights that people with O blood type can donate to anyone, making them the

most versatile donors.

9.18 What Is an Early Kidney Transplant?

An early kidney transplant is when a person receives a kidney transplant before starting dialysis treatment. While kidney transplants are often performed after dialysis has begun, some individuals in good health and with timely donor availability can undergo a transplant earlier. This approach is called an "early kidney transplant."

9.19 What Is Paired Kidney Donation?

Paired kidney donation happens when a donor's kidney is incompatible with their intended recipient due to blood type or other factors. In this case, two or more donor-recipient pairs are matched so that each recipient receives a kidney from another donor in the group who is compatible with them. This process allows more people to receive life-saving kidney transplants.

The image below illustrates this. Mismatch Pair Kidney Donation Blood type Pair 1: Blood type A+ Recipient - 1 B+ Donor - 1

Pair 2: Blood type Blood type B+

A+ Recipient - 2 Donor - 2

This may involve transplanting a kidney from a non-complaint partner to another partner. This can be called "Exchange" between peers. This is the procedure where kidney donor number-1 donates kidney to recipient number 2.

9.20 How long should kidney transplant recipients take immunosuppressants?

These pills should be taken throughout life to prevent kidney resistance. The dosage of pills can be reduced, but not stopped.

Kidney Transplantation — Video Guide
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Chapter 10

Chapter 10

Nephrotic Syndrome

10.1 What is nephrotic syndrome?

Nephrotic syndrome is a type of kidney disorder. This is a condition in which too much protein is excreted in your urine. Nephrotic syndrome is usually caused by damage to clusters of small blood vessels that filter waste and excess water from the blood in your urine. Due to the release of this protein in the urine, the body reacts to inflammation. Especially your feet and ankles and face will swell. This can lead to various health problems.

10.2 What causes nephrotic syndrome?

Nephrotic syndrome is not a kidney disease caused by a specific cause. It can be caused by any condition that damages the kidney filter units (Glomerulus) and causes excess protein to be excreted in the urine. Nephritis and kidney diseases that cause nephrotic syndrome only affect the kidneys. Common disorders such as diabetes and lupus do not cause nephrotic syndrome, but affects other parts of the body as well. It can also occur as a side effect of some medications and some types of malaria infection.

10.3 What are the symptoms of nephrotic syndrome?

If you have nephrotic syndrome, you might notice:

  • Swelling in the body: This is common around your eyes, ankles, and feet.
  • Foamy urine: Your urine might look bubbly because of too much protein being lost from your body.
  • Fluid buildup: Extra fluid in your body can make you gain weight.
  • Fatigue and loss of appetite.

10.4 Can nephrotic syndrome be cured?

Yes, nephrotic syndrome can usually be treated, but it depends on what's causing it. The main goals of treatment are to stop the loss of protein through urine and to help your body get rid of extra fluid.

10.5 Is nephrotic syndrome genetic?

Nephrotic syndrome happens when the tiny blood vessels in your kidneys get damaged and can't filter out extra protein properly. This causes protein to leak into your urine (called proteinuria), which leads to low protein levels in your blood (hypoalbuminemia). If you have nephrotic syndrome, your body might feel weak, develop high blood pressure, and be more prone to infections. Additionally, there is a risk of kidney damage, which can be especially concerning during pregnancy.

Nephrotic syndrome can sometimes be caused by genetic disorders, such as hereditary congenital nephrotic syndrome or steroid-resistant nephrotic syndrome. These conditions result from mutations in specific genes that are inherited from a person's parents. However, not all cases of nephrotic syndrome are hereditary. It can also develop due to autoimmune disorders, infections, or other underlying health problems. In some cases, the exact cause may not be linked to inheritance but rather to a genetic predisposition.

If you're concerned about your risk of developing nephrotic syndrome, it's important to share your medical and family history with your doctor. They can perform tests to check if you're at risk and suggest ways to prevent the condition.

10.6 What tests are done to diagnose nephrotic syndrome?

  1. Urinalysis
  2. Protein content in urine

3.24 -hour urinary protein test

  1. Urine protein-to-creatinine ratio
  2. Blood tests
  3. ASO titre test
  4. Kidney biopsy

10.7 How often is surgery needed for nephrotic syndrome?

Surgery is not commonly required for nephrotic syndrome. Treatment depends on the cause and typically includes medications and lifestyle changes. If surgery or other advanced treatments are necessary, your doctor or urologist will guide you based on your specific condition.

10.8 What are the complications of nephrotic syndrome?

Nephrotic syndrome can lead to the following problems:

  • High blood pressure
  • Acute kidney injury (sudden loss of kidney function)
  • Infections (due to a weaker immune system)
  • Weakness or fatigue

10.9 What foods should patients with nephrotic syndrome avoid if they have diarrhea?

When a person with nephrotic syndrome experiences diarrhea, it's best to avoid:

  • Processed foods
  • Processed meats
  • Full-fat dairy products
  • Fried foods

10.10 What is the recommended diet for nephrotic syndrome?

  • Low salt: Reducing salt in food helps to lower water retention in the body.
  • Monitor water intake: If there is significant water retention, the doctor may advise limiting fluid intake.
  • Increase protein: Since protein is lost in the urine, it's important to include proteinrich foods like eggs, lean meat, fish, and legumes, as recommended by your doctor or dietitian.
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Chapter 11

Chapter 11

Polycystic Kidney Disease

11.1 What is polycystic kidney disease?

Polycystic kidney disease (PKD) is a condition that runs in families. In this disorder, fluid-filled cysts form in groups, mostly in the kidneys. Over time, these cysts can cause the kidneys to enlarge and lose their ability to work properly.

11.2 What causes polycystic kidney disease?

PKD is primarily a genetic condition, meaning it is passed down from parents to children through their genes. In rare cases, it can develop without any family history, happening spontaneously due to new genetic changes.

11.3 What is complicated polycystic kidney disease?

Complicated polycystic kidney disease refers to a more advanced stage of the condition where the cysts grow larger and more numerous over time. This leads to an increased risk of the kidneys losing their ability to function effectively, potentially causing serious health problems.

11.4 What are the two types of polycystic kidney disease?

Polycystic kidney disease (PKD) comes in two main types, caused by different genetic changes:

  1. Autosomal Dominant Polycystic Kidney Disease (ADPKD):

This is the more common type. Symptoms usually appear between the ages of 30 and 40.

  1. Autosomal Recessive Polycystic Kidney Disease (ARPKD):

This is a much rarer form of PKD. It often affects children and can cause symptoms early in life.

11.5 Can polycystic kidney disease be cured?

Currently, there is no cure for autosomal dominant polycystic kidney disease (ADPKD), and it's not possible to completely stop cysts from forming in the kidneys. However, medications like tolvaptan can slow down the growth of cysts and reduce the risk of kidney failure. While these treatments don't cure the disease, they can help manage its progression and complications.

11.6 What are the common complications of autosomal dominant polycystic kidney

disease (ADPKD)?

People with ADPKD may experience:

  • Infections in kidney cysts
  • Bleeding or rupture of kidney cysts
  • Urinary tract infections (UTIs)
  • Kidney stones
  • Gradual loss of kidney function as cysts grow larger.

11.7 Can I live a normal life with polycystic kidney disease?

Yes, it is possible to live a good quality of life with polycystic kidney disease (PKD) by managing the condition effectively. The main focus is on controlling the disease and maintaining overall health. Eating a healthy diet with low salt, staying physically active, and learning ways to manage pain, if any, are essential steps. It's also important to stay in regular contact with your healthcare providers to find the best treatments and lifestyle adjustments. By taking these measures and addressing complications early, many people with PKD can lead fulfilling lives.

Polycystic Kidney Disease — Video Guide
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Chapter 12

Chapter 12

Urinary Tract Infection

12.1 What are the main causes of urinary tract infections?

Urinary tract infections (UTIs) happen when bacteria enter the urinary tract, usually through the urethra (the tube that allows urine to exit the body). Women are at higher risk of UTIs because their urethra is shorter than men's, making it easier for bacteria to reach the bladder or kidneys. In rare cases, UTIs can occur if an infection in another part of the body spreads to the kidneys through the bloodstream.

12.2 What are the symptoms of a urinary tract infection?

  • Burning sensation during urination
  • Irritation or discomfort while urinating
  • Frequent urination but with very little output
  • Cloudy or unclear urine
  • Red, pink, or cola-coloured urine (this may indicate blood in the urine)
  • Strong or unpleasant smell in the urine.

12.3 What is the best treatment for urinary tract infections?

Antibiotics are the most common treatment for urinary tract infections (UTIs). The type of antibiotic and the duration of treatment depend on your overall health and the specific bacteria causing the infection. Your doctor will guide you on the right medication and how many days you should take it.

12.4 How long does it take for a urinary tract infection to heal?

Most UTIs can be completely cured with proper treatment. Symptoms of a bladder infection often improve within 24 to 48 hours after starting antibiotics. However, in some cases, it may take a week or more for all symptoms to go away.

12.5 What happens if a urinary tract infection is not treated for 2 weeks?

If a UTI is left untreated, it can spread to other parts of the body, including the kidneys, and may become severe or life-threatening. Untreated infections can cause complications like blood in the urine, worsening symptoms, or a kidney infection. It is essential to seek treatment promptly to avoid these risks.

12.6 How do you know if a urinary tract infection has spread to the kidneys?

When a UTI spreads to the kidneys, the symptoms become more severe. You may experience fever, chills, fatigue, or weakness, along with pain in the lower back or side near the spine. Nausea and a general feeling of being unwell are also common. These symptoms, combined with the usual signs of a UTI, indicate that the infection may have reached the kidneys.

12.7 If there is irritation after urination, how can it be treated?

There are several ways to reduce discomfort during or after urination. Drinking plenty of water helps flush out the urinary tract and reduces irritation. Herbal remedies may also provide relief. In some cases, medications or pain-relief pills can be used. If the irritation persists or is caused by a more serious issue, prescription medication may be necessary, so consulting a doctor is important.

12.8 What should you avoid with a urinary tract infection?

  • Avoid foods and drinks that can worsen UTI symptoms, such as caffeine, alcohol, and spicy foods.
  • Don't delay seeing a doctor if you have irritation or discomfort during urination.
  • Never stop taking antibiotics before completing the prescribed course, even if you feel better.
  • Avoid drinking too little water, as staying hydrated is key to flushing out the infection.
  • Don't hold your urine; delaying urination can make the infection worse.

12.9 How much water should you drink to flush out a UTI?

If you have a UTI, it is generally recommended to drink 6 to 8 pints (1.5 to 2 liters) of water per day. Staying well-hydrated helps flush out bacteria from the urinary system. Keep drinking water until your urine is clear and flows with good pressure, as this is one of the quickest ways to recover.

12.10 What can you eat when you have a urinary tract infection?

Foods like yogurt and pickles contain beneficial bacteria (probiotics) that can help fight infections and support recovery. Eating fiber-rich foods like bananas, beans, lentils, nuts, oats, and whole grains can be very helpful. They help clean out bad bacteria from your body and keep you healthy.

Urinary Tract Infection (UTI) — Video Guide
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Chapter 13

Chapter 13

The Difference between Nephrology and Urology

13.1 Are nephrologists and urologists the same?

No, nephrologists and urologists are not the same, as their medical roles are different. A nephrologist is a doctor who specializes in diagnosing and managing kidney-related diseases through medications and other non-surgical treatments. They focus on how the kidneys function and address issues like chronic kidney disease, kidney infections, and high blood pressure related to kidney problems.

A urologist, often referred to as a kidney surgeon, specializes in surgical and medical treatments for the urinary system, including the kidneys, bladder, ureters, and urethra. They focus on fixing physical problems like blockages, stones, or tumors in these areas, which may involve surgery.

13.2 Can a urologist treat kidney disease?

Yes, urologists can treat certain kidney problems that require surgery. For example, they can remove kidney stones, fix blockages in the urinary system, or remove cancer in the kidneys or bladder. These procedures can help improve how the kidneys work. However, if the kidney problem is caused by infections, protein-related issues (like nephrotic syndrome), or other medical conditions, a nephrologist will take care of it, often without surgery.

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Chapter 14

Chapter 14

Urology

14.1 What is Urology?

Urology is a branch of medicine that focuses on diseases of the urinary tract and male reproductive system. These urologists treat common obstructive diseases of the urinary tract.

14.2 What are common urological problems?

  • Urinary status
  • Urinary tract infection
  • Kidney and ureteral stones
  • Overactive bladder
  • Pelvic floor dysfunction, spasms
  • Erectile dysfunction
  • Prostate problems
  • Prostate cancer
  • Prostate infections

14.3 What are the symptoms of these kidney problems?

Blood in urine (red or pink urine)
Pain in the back or hips
Needing to urinate frequently
Pain or burning while urinating
Uncontrolled leakage of urine

14.4 How do I know if I have kidney stones?

The symptoms of kidney stones include:

  • Intense, sharp pain below the ribs and in the back
  • Pain that spreads to the abdomen and pelvis
  • Pain that comes and goes in waves and changes in intensity
  • Discomfort or burning during urination
  • Feeling sick, with nausea or vomiting
  • Fever and chills if an infection is present

14.5 What does kidney stone pain feel like?

Kidney stone pain is usually sharp and intense, starting on one side of the lower back or abdomen. The pain can move from the upper abdomen down to the lower abdomen or even into the groin. You might feel irritation or pain when urinating and may also feel like you haven't completely emptied your bladder. As the pain gets worse, it can lead to nausea and vomiting.

14.6 What causes kidney stones?

Kidney stones form when your urine has too many substances like calcium, oxalate, or uric acid that can form crystals. Normally, your urine contains chemicals that prevent these crystals from sticking together, but if these protective chemicals are low, kidney stones can develop.

14.7 What can be done to pass kidney stones?

  • Drink plenty of water: Drinking 2 to 3 liters of water daily helps dilute your urine and flush out kidney stones more easily.
  • Take pain relievers: Passing a stone can be painful, so painkillers can help ease the discomfort and support the process.
  • Follow medical treatment: Your doctor may prescribe specific medications to help dissolve or pass the stone. Be sure to take them as instructed.

14.8 What are the common causes of kidney stones?

The most common type of kidney stone is made of calcium oxalate. These stones form when oxalate, a substance created when you eat certain starchy foods, combines with calcium in the urine. Dehydration (not drinking enough water) and consuming too much salt can make it easier for these substances to stick together and form stones. When the urine becomes too concentrated, it creates the perfect environment for kidney stones to develop.

14.9 What drinks can cause kidney stones?

Some drinks, like cola, artificially flavored fruit punches, and sweetened teas, can increase the risk of kidney stones. These drinks often contain high levels of fructose (a type of sugar) and phosphoric acid, which can lead to the formation of kidney stones.

14.10 Does dehydration cause kidney stones?

Yes, dehydration is one of the most common causes of kidney stones. When you don't drink enough water, your body produces less urine, which becomes more concentrated with minerals like calcium and oxalate. This creates an ideal environment for kidney stones to form. Staying well-hydrated helps reduce this risk.

14.11 What foods can cause kidney stones?

Certain foods can increase the risk of kidney stones, including:

  • High-salt foods
  • High-oxalate foods
  • Animal proteins
  • Sugary desserts
  • Wine

14.12 How can kidney stones be prevented from coming back?

You can reduce the chances of kidney stones returning by making some dietary changes and staying hydrated. Here are some tips:

  • Drink plenty of water: Aim to drink 2.5 to 3 liters of water daily. Staying hydrated helps flush out minerals and prevents stone formation. Drinking enough water can also help pass small stones before they grow larger.
  • Try healthy drinks: Juices like orange, cranberry, apple, or water mixed with lemon juice are beneficial. These fluids help lower the risk of kidney stone formation.
  • Limit high-oxalate foods: Reduce intake of foods like spinach, tea, chocolate, and sugar, which are high in oxalates. Opt for foods lower in oxalates, such as cashews or soy products.
  • Dairy in moderation: Milk, cheese, and butter contain calcium, which can be tricky for people prone to kidney stones. While reducing calcium intake might help some people, there's no need to completely avoid dairy if consumed in normal amounts.
  • Avoid certain seafood: Fish like sardines and tuna are high in purines, which can raise uric acid levels and increase the risk of kidney stones. Limit these foods if you are prone to stones.
  • Control animal protein intake: Reducing foods like meat, poultry, eggs, and fish can help lower the amount of acid in your urine. A high level of acid increases the chance of stone formation, so eating less animal protein is recommended.
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Chapter 15

Chapter 15

Benign Prostate Hyperplasia

15.1 What is the prostate gland, and what does it do?

The prostate gland is a small organ in men, located at the base of the bladder. It surrounds the tube (urethra) that carries urine from the bladder to the outside of the body. About the size of a walnut, the prostate plays an important role in reproduction by producing a fluid that mixes with sperm to help it travel through the urethra during ejaculation.

15.2 What is benign prostate gland swelling?

Benign prostate swelling, also called Benign Prostate Hyperplasia (BPH), is an enlargement of the prostate gland that is not cancerous. This is a common condition as men age, where the prostate grows slightly larger over time.

In some cases, the enlarged prostate can press against the urethra, which can lead to problems like:

  • Difficulty starting urination
  • Weak urine flow
  • Feeling that the bladder hasn't emptied completely.

15.3 What Are the Symptoms?

Symptoms usually start after the age of 50 and develop gradually over the years. The main symptoms include:

  • Waking up frequently at night to urinate.
  • Slower or less frequent urination.
  • Even when the bladder feels full, only a small amount of urine comes out.
  • Difficulty in urinating and a feeling of not completely emptying the bladder.
  • A dribbling or weak flow of urine.
  • After urinating, noticing wet spots on underwear due to leftover drops.

15.4 What Are the Consequences?

If prostate inflammation worsens, it can lead to more serious issues, including:

  • Stopping urination altogether.
  • Urine staying in the bladder even after trying to empty it, which is called Post Void

Residual Volume.

  • The bladder becoming weaker and unable to fully empty itself.
  • Long-term blockage can put pressure on the kidneys, potentially leading to kidney

failure.

  • Kidney stones and urinary tract infections becoming more common.

15.5 How Is This Swelling Diagnosed?

Doctors use several methods to find out if there is a problem with the prostate:

Finger Examination: The doctor uses a gloved finger to feel the prostate through the anus to check its size and shape.

Ultrasound: A scan shows the size and condition of the prostate and helps measure how much urine remains in the bladder after urinating.

PSA Test (Prostate-Specific Antigen): This blood test helps determine if there is a risk of prostate cancer.

15.6 How Can It Be Treated?

Treatment depends on how severe the symptoms are.

Lifestyle Changes (for mild symptoms):

  • Try to urinate more often to keep the bladder empty.
  • Avoid coffee and alcohol as they can make symptoms worse.
  • Limit drinking too much water, especially before bedtime.
  • Stop taking over-the-counter allergy medicines without consulting a doctor.
  • Treat constipation, as it can worsen symptoms.

Medications:

Anti-inflammatory tablets for prostatitis may help. Always follow the advice of a urologist and take the medication as prescribed.

Surgical Options (for severe cases):

Urethral Resection of the Prostate: This involves removing part of the prostate through the urethra.

Transabdominal Resection of the Prostate: A surgical method to remove part of the prostate through the abdomen. Yes, these symptoms can often be treated effectively to improve your quality of life. It's important to consult a urologist to determine the best treatment plan for your condition.

15.7 What Causes Prostate Problems?

Age is one of the biggest risk factors for prostate cancer.

  • If you are white and have no family history of the disease, your risk is about 50% lower.
  • If you are Black and have a close family member with prostate cancer, your risk is higher.
  • Most cases of prostate cancer are diagnosed in men aged 65 or older.

15.8 What Are the Warning Signs of Prostate Issues?

In the early stages, prostate cancer may not cause any symptoms. However, in more advanced stages, you might notice:

  • Trouble or straining to urinate.
  • A weaker or slower urine flow.
  • Blood in the urine or semen.
  • Bone pain.
  • Unexplained weight loss.
  • Changes in erections.

15.9 Can Prostate Cancer Be Cured?

Yes, prostate cancer can be cured if it is detected and treated early.

  • Most prostate cancer cases (about 90% higher) are detected in the early stages. Thus, the treatment performed for these tumours gives good results.

15.10 Is It Possible to Live Without a Prostate?

Yes, it is possible to live without a prostate. After its removal, urine from the bladder will flow directly out of the body. However, men without a prostate may need support or guidance to manage urination, such as learning alternative methods or seeking counselling for urinary control.

15.11 What Is the Life Expectancy After Prostate Removal?

Life expectancy after prostate removal (prostatectomy) depends on several factors, including:

  • The stage of cancer at the time of surgery.
  • The patient's overall health.
  • Whether additional treatments, such as radiation or chemotherapy, are needed.

If the cancer is detected early and hasn't spread beyond the prostate, the outlook is excellent. According to the American Cancer Society:

For cancer confined to the prostate: The 5-year survival rate is nearly 100%. For cancer that has spread to other parts of the body: The 5-year survival rate drops to about 30%.

In summary, men who undergo early treatment for localized prostate cancer usually live long and healthy lives. For men with advanced prostate cancer, the prognosis may be more uncertain, depending on the extent of the spread and the effectiveness of additional treatments.

15.12 How to avoid prostate cancer?

  • Eat healthy food
  • Maintain a healthy weight
  • Do regular exercise
  • Stop smoking
  • If you drink alcohol, reduce the amount
  • Walk in the sun to increase vitamin
  • *Be sexually active
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Chapter 16

Chapter 16

Basic Laboratory Tests for Kidney Damage and Surgery

  1. Blood urea test
  2. Test of creatinine in blood
  3. Nodal filtration rate (GFR)
  4. Full examination of urine
  5. Urinary Ultrasound (abdominal scan)
  6. Kidney biopsy
  7. Serology
  8. Iron measurements
  9. Parathyroid size
  10. Bleeding calcium, phosphorus amount
  11. Examination of whole blood cells
  12. Blood electrolyte measurement
  13. HLA genotyping Tests for Kidney Transplantation
  14. Bleeding Tacrolimus dose (when needed)
  15. Special blood tests (as required)

16.1 Blood Urea

16.1. 1. Why test it?

This test is used to check how well your kidneys are working. It helps doctors decide if you need treatments like dialysis and can show if there are any kidney problems or damage.

16.1. 2. When is it needed?

You may need this test if your kidneys might be having problems. It's especially important for people with long-term health issues like diabetes or high blood pressure, as these conditions can affect kidney function. Regular testing helps keep track of kidney health.

Normal Levels: Urea levels should be between 15 and 40 mg/dl.

16.2 Serum Creatinine

16.2. 1. Why test it?

This test is used to check how well your kidneys are working and to monitor the risk of kidney disease.

16.2. 2. When is it needed?

It's needed not only if kidney problems are suspected, but also for people with chronic conditions like diabetes or high blood pressure. Regular testing helps monitor kidney function and can be used to calculate the Glomerular Filtration Rate (GFR), a key indicator of kidney health. Normal Values: Serum Creatinine ­ 0.6 to 1.3 mg/dl

16.3 Urine Microalbumin (Microprotein in Urine)

16.3. 1. When should it be tested?

If you have diabetes or high blood pressure, it's a good idea to get this test done once a year.

16.3. 2. When is it needed?

  • For people with type 2 diabetes (under 70 years old) and for children or adults over 12 with diabetes, this test should be done yearly to check for kidney problems.
  • For people with high blood pressure, the test can be done as recommended by their doctor.

16.3. 3. What is albumin? Why test it?

Albumin is a protein made by your liver, and it's normally found in your blood in large amounts. In healthy kidneys, albumin doesn't pass into the urine. However, if your kidneys are damaged or not working well, they start to leak albumin into the urine. The presence of more albumin in the urine can be an early sign of kidney problems, which could eventually lead to kidney failure if not caught early. This is especially important for people with chronic conditions like diabetes and high blood pressure.

Doing the urine microalbumin test regularly can help catch kidney issues early and prevent serious damage.

Normal Values: Urine Microalbumin ­ 0.0 to 25 mg/dl

16.4 24-Hour Urine Protein Test

16.4. 1. What does it measure? Why test this?

This test measures how much protein is being lost in your urine over a full 24-hour period. The amount of protein in your urine can help doctors understand the cause of kidney problems, and it can guide further testing if needed.

16.4. 2. When should it be tested?

Your doctor may recommend this test if you have conditions like nephrotic syndrome (a kidney disorder), or if you have unexplained swelling in your legs or elsewhere, which could indicate kidney issues.

16.4. 3. How is it done?

  • Start by urinating in the morning, but don't collect this first urine. Note the time (for example, 8 AM).
  • For the next 24 hours, collect all of your urine in a special container that your doctor will give you.
  • The next morning, at the same time (for example, 8 AM), collect your first urine of the day and add it to the container. This marks the end of the 24-hour period.
  • After that, close the container tightly and take it to the testing center as soon as you can.
  • Be sure to label the container with your name, the date, and the time.

This test measures how much protein is passed in the urine over 24 hours. Normally, about 150 grams of protein in 24-hour urine is tested.

16.5 Urinalysis

16.5. 1 Why is this test done?

It helps to identify problems with the kidneys, like damage, infections, stones, or when they aren't working properly.

16.5. 2 When should this test be done?

  • During routine health checkups.
  • If you have symptoms like:

o Pain in the lower belly or back. o Blood in the urine. o Burning sensation during urination.

  • During pregnancy.
  • Before certain surgeries.
  • When admitted to the hospital.

16.5. 3 What is checked in this test?

  • Sugar levels in urine.
  • Protein levels.
  • The concentration of urine (density).
  • Acidity (pH).
  • Substances like bilirubin, urobilinogen, ketones, and nitrogen compounds.
  • White blood cells
  • Red blood cells.
  • Crystals
  • Germs or tissues.

Explanation:

  • Glucose: Normally, glucose is not found in urine. However, when blood sugar levels exceed 180 mg/dL, glucose spills into the urine. It is recommended to check blood sugar levels during these instances.
  • Protein: The presence of protein in the urine indicates a potential issue with the kidneys.
  • Concentration level: This reflects the kidney's ability to filter properly.
  • Acidity (pH): Increased acidity in urine can contribute to infections and the formation of kidney stones.
  • Bilirubin and urobilinogen: These are indicators of liver function and help in diagnosing the type of jaundice.
  • Ketones: Found in the urine when blood sugar becomes dangerously high, often in cases of uncontrolled diabetes.
  • Nitrites: Their presence indicates a bacterial infection.
  • White blood cells: These appear in urine when there is an infection in the urinary tract.
  • Blood cells: The presence of blood cells in urine suggests blood in the urine, which may be due to injury, stones, or other underlying issues.
  • Germs or tissues: Some germs may be accompanied by tissue fragments, which can provide additional clues.
  • Crystals: These may help identify the type of kidney stone present.

16.6 Whole Blood Cytology (Complete Hemogram)

16.6. 1 Why is this test performed?

  • To check your blood for hemoglobin levels, red blood cells, white blood cells, and platelets, which are essential for blood clotting.
  • To identify and differentiate between the various types of white blood cells and assess their proportions in the blood.
  • To detect abnormalities in blood, including issues with the production, functioning, and destruction of blood cells.

16.6. 2 When should this test be done?

  • When there is a suspicion of a deficiency in blood cells, damage to blood cells, or reduced production of blood cells.
  • To evaluate the production and development of blood cells and ensure they are fully formed and functional.
  • In cases of anemia, to monitor hemoglobin levels continuously.

16.6. 3 What tests are included in a Complete Blood Count (CBC)?

  • Hemoglobin test: Measures the oxygen-carrying protein in the blood.
  • Total leukocyte count: Assesses the total number of white blood cells.
  • Hematocrit test: Evaluates the proportion of red blood cells in the blood.
  • Total white blood cell count: Determines the overall white blood cell levels.
  • Differential white blood cell count: Breaks down the types of white blood cells and

their respective proportions.

  • Platelet count: Measures the number of platelets responsible for blood clotting.
  • Average volume of red blood cells (Mean Corpuscular Volume, MCV)
  • Average number of dead cells
  • Special tests for kidney diseases

16.7 Abdominal and Urinary Tract Imaging (Ultrasonogram of Abdomen & KUB Area)

An ultrasound provides detailed images of the organs within the abdomen. It is used to examine the structure, size, and any blockages in the affected organs, such as:

  • Liver and spleen
  • Kidneys, ureters, and bladder
  • Gallbladder and pancreas

It also aids in identifying abnormalities in the uterus and other related structures.

16.8 Examinations for Transplant Surgery

A comprehensive set of tests is performed to ensure the patient is fit for transplant surgery. These include:

  1. Complete Blood Count (CBC): To check for anemia, infection, or other blood-related issues.
  1. Erythrocyte Sedimentation Rate (ESR): Indicates inflammation in the body.
  2. Blood Sugar Tests:

o Fasting blood sugar (on an empty stomach). o Postprandial blood sugar (after a meal).

  1. Degradation Control Tests: Additional metabolic and regulatory evaluations.
  2. Fasting Lipid Profile: Measures cholesterol and other fat levels in the blood.
  3. Complete Urinalysis: Evaluates overall kidney health and detects abnormalities in the urine.
  4. Protein in Urine and Creatinine Levels: Assesses kidney function.
  5. Blood Tests: Includes urea, creatinine, sodium, and potassium levels, which are critical markers of kidney function.
  6. Blood Uric Acid Level: To monitor uric acid levels, which can indicate kidney or metabolic issues.
  1. Liver Function Tests (LFTs): To assess liver health before surgery.
  • Thyroid Hormone Levels
  • Jaundice Markers:

o Jaundice Germ (Type C) o Jaundice Severity (Type B) o AIDS and Viral Infections (e.g., Cytomegalovirus)

  • Chest Pain Evaluation: Eclre
  • Cardiovascular Examination: o ECG (Electrocardiogram) o Echocardiogram o Ultrasound Examination
  • 24-Hour Urinary Creatinine Excretion

16.9 Other Special Tests

  • Radioisotope Renogram
  • Angiography
  • Blood Type Compatibility Tests

16.10 Advice from Other Medical Professionals

  • Cardiologist Consultation
  • Urologist Consultation
  • Psychiatric Counseling
  • Dentist's Advice
  • Cervical Specialist Consultation
  • ENT (Ear, Nose, and Throat) Specialist Consultation
  • Ophthalmologist Examination
  • Gastrointestinal Examination
  • Pulmonologist Consultation
  • Other Consultations and Tests as Required

Note- Before the transplant surgery, this consultation and examination is done to see if the above organs of the body are functioning well and if there are any infections.

  1. Diet
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Chapter 17

Chapter 17

Food Habits

17.1 Carbohydrates

Carbohydrate is one of the three important macronutrients needed by the body. The others are fat and protein. These macronutrients are the most essential and fundamental part of our body. Without these, the human body cannot function smoothly or healthily. Among these, carbohydrates are considered to be the most important.

17.1. 1 What is Carbohydrate?

Carbohydrate can be described as a molecule that provides energy to humans. Glucose, an important component of carbohydrates, powers the body's movements. These carbohydrates are mostly found in plant-based foods. They are also present in milk and milk products in the form of lactose.

Carbohydrates are usually abundant in bread, potatoes, and rice. They are also present in fruits, where this form of carbohydrate is called fructose. Carbohydrates play a vital role in the nutrients required for a healthy life.

In our body, reserve energy is stored in the form of glycogen, not carbon dioxide. When needed, this glycogen is broken down to provide energy. Specifically, one gram of glucose provides four calories of energy, which is essential for powering the body's functions.

Carbohydrates are present in all tissues of the body. They are abundant not only in the skin, muscle fibers, cartilage, bones, and connective tissues but also in the nervous system.

Types of Carbohydrates in Foods

Carbohydrates in foods exist in various forms, including:

  • Dietary Fiber: This is a type of carbohydrate that is not easily digestible. It is found in abundance in fruits, vegetables, nuts, beans, and whole grains. Fiber supports healthy digestion and helps prevent constipation.
  • Total Sugar: This refers to sugars naturally present in milk and dairy products, as well as sugars commonly found in sweets. These sugars are easily digested and completely absorbed by the body.
  • Sugar Alcohols: Sugar alcohols are another form of carbohydrate. They are low-calorie alternatives to natural sweeteners and sugars. Unlike regular sugars, these are not fully absorbed by the body. They are often used in reduced-calorie baked goods and sweeteners, as their preparation involves adding alcohol to modify their structure.
  • Starch: Starch, such as glucol, is a type of carbohydrate composed of large numbers of molecules linked together. It is classified as a compound sugar and is the most common carbohydrate found in the foods we consume. Starch is abundant in wheat, rice, potatoes, corn, and cassava and plays a vital role in these foods.
  • Types of Carbohydrates: Carbohydrates are linked in various ways, forming different types:

o Monosaccharides: The basic units of carbohydrates, such as glucose, fructose, galactose, and xylose.

o Disaccharides: Formed when two monosaccharides combine. Examples include maltose, sucralose, and lactose.

o Polysaccharides: Made from multiple monosaccharides linked together. Examples include starch, collagen, and cellulose.

Single and double sugars are often referred to as "sugar" in common terms.

Carbohydrates You Need

Carbohydrates are essential for everyone. Their importance lies in the multiple roles they play in the body:

  • The primary function of carbohydrates is to provide energy. In many countries, carbohydrates contribute to approximately 70% of daily energy intake.
  • Proteins can effectively perform their role in body development and repair only when there is an adequate amount of carbohydrates available to meet energy needs.
  • Carbohydrates like fiber help the intestines absorb more water, prevent constipation, and support healthy digestion.
  • When the amount of carbohydrates in the body decreases, the body uses its reserves to produce energy. This process can increase acidity levels in the body, leading to potential health risks.
  • Carbohydrates are essential for producing glycoproteins that boost immunity, lipids required for the cells of the nervous system, and amino acids that support chemical activities in the body.

In Summary: Carbohydrates provide multiple benefits:

  • Serve as an excellent source of energy.
  • Enhance digestion and improve digestive efficiency.
  • Prevent muscle fatigue while supporting muscle development and movement.
  • Prevent the formation of ketones.
  • Aid in the creation of immune-supporting molecules.

Thus, carbohydrates are indispensable for maintaining a healthy life. However, it is important to note that consuming them in excess can lead to adverse effects.

Obesity and Carbohydrates In the current era of globalization, the number of people experiencing obesity has increased significantly. The overconsumption of carbohydrates is one of the main contributing factors to this issue. Other factors may also play a role in obesity, but excessive carbohydrate intake remains a primary concern.

  • Lack of physical exercise
  • Excessive consumption of fast food and junk food
  • Overeating
  • Insufficient sleep
  • Hereditary genetic factors
  • Stress, which can also contribute to weight gain

17.1. 2 Steps to Avoid Obesity and Maintain Health

Choose foods rich in natural, unprocessed carbohydrates. Include more vegetables, legumes, whole grains, and nutritious seeds like nuts in your diet. Avoid fast food as much as possible. Practice moderation in portion sizes when eating.

Key Points to Remember

  • Carbohydrates are nutrient-rich molecules that provide energy to the body.
  • It is essential to understand the differences between simple and complex carbohydrates:

o Simple carbohydrates: These are low in nutrients and do not effectively support digestion. Their intake should be controlled.

o Complex carbohydrates: These are highly nutritious, sustain energy for longer periods, and can be included in the diet in larger quantities.

Carbohydrates in a Diabetic Diet For individuals with diabetes, it is essential to reduce the amount of carbohydrates in the diet. This helps in managing weight and maintaining better control over blood sugar levels.

A single serving of a carbohydrate-based diet provides approximately 60-100 calories. If you are overweight, reducing the number of carbohydrate-rich meals can help manage your weight. On the other hand, if you are underweight, increasing carbohydrate intake may be beneficial. For individuals with diabetes, controlling carbohydrate consumption is critical for maintaining stable blood sugar levels. If you are trying to manage your weight or have diabetes, consulting a dietitian can help you determine the right amount of carbohydrates for your specific needs. A dietitian can provide personalized advice on your daily carbohydrate requirements.

Carbohydrates in Kidney-Friendly Diets Carbohydrates play a unique role in diets designed for individuals undergoing dialysis.

  • Carbohydrates and Hemodialysis:

For those receiving in-center or home hemodialysis, carbohydrate requirements typically make up about half of the daily diet. This translates to approximately 40- 60% of daily calorie intake coming from carbohydrates. For example: If your daily calorie requirement is 2,000 calories, 800-1,200 calories should come from carbohydrate-rich foods.This equates to approximately 200-275 grams of carbohydrates per day.

  • Carbohydrates and Peritoneal Dialysis:

If you are undergoing peritoneal dialysis, your carbohydrate needs are generally lower compared to those on hemodialysis. The required amount depends on the glucose concentration in your dialysis solution and the type of peritoneal dialysis you are using, whether continuous or automated.

Understanding and adjusting carbohydrate intake based on your medical condition and treatment type is essential for optimal health.

The number of calories your body absorbs can vary. Specifically, you can determine how many calories are absorbed from one liter of peritoneal dialysis fluid, which helps in managing your dietary and energy needs.

Dextrose CAPD Calories APD Calories Concentration Absorbed Absorbed

Ratio 31-36 calories/1 20-26 calories/liter

1.5 % liter 34-43 calories/lite

58-73 calories/liter

2.5 % 51-60 calories/1

liter

4.25 %

87-102 calories/1 liter

17.2 Protein

Protein is one of the key macronutrients required for maintaining good health. Although it is vital, its availability in nutrient-dense foods varies, meaning you may not need as much as you think. Understanding the fundamentals of protein and incorporating healthy protein sources into your diet is crucial for overall well-being.

17.2. 1 What is Protein?

Protein is a fundamental component of the human body. It is present in muscles, bones, skin, and almost every organ or tissue. Protein plays several critical roles, including: Creating enzymes that drive chemical reactions in the body. Forming hemoglobin, which carries oxygen in the blood.

There are at least 10,000 different types of proteins in your body, each contributing to its structure and function. Proteins essentially make up who you are and are indispensable for life.

Proteins are made up of more than twenty fundamental building blocks known as amino acids. Since the body does not store amino acids, it produces them in two ways: either by synthesizing new ones or modifying existing ones.

Nine amino acids are classified as essential amino acids because they cannot be produced by the body and must be obtained through diet. These include: Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan, Valine.

Functions of Proteins:

  • Proteins are vital for building the body, supporting growth, repairing tissues, and maintaining overall body structure.
  • All enzymes, many hormones, transport carriers, and immunoglobulins (antibodies) are made of proteins.
  • Proteins help regulate normal blood pressure, blood clotting, and muscle movement.
  • Although not their primary function, proteins can provide energy when dietary caloric intake is insufficient. Each gram of protein provides 4 calories.
  • Proteins are an important source of nitrogen, sulphur, and phosphorus, which are critical for various physiological functions.

17.3 Nitrogen Balance

Positive Nitrogen Balance:

  • This is the stage where nitrogen intake exceeds output.
  • A large amount of nitrogen is retained in the body. So the net increase in body protein is accordingly.
  • A positive nitrogen balance is seen in growing children, pregnant women, or those recovering from serious illness.

Negative Nitrogen Balance:

  • This is the stage where nitrogen output is greater than intake.
  • Nitrogen levels are lost from the body, reducing body protein.
  • Prolonged negative nitrogen balance can be life-threatening.
  • This condition is seen in children suffering from kwashiorkor or marasmus protein

deficiency.

  • A negative nitrogen balance can occur if the diet is insufficient in protein (a particular

amino acid is depleted) and tissue destruction or severe disease occurs.

  • Growth-stimulating hormone and insulin promote positive nitrogen balance.

Corticosteroids, on the other hand, adjust to negative nitrogen balance.

  • Cancer and uncontrolled diabetes adapt to negative nitrogen balance.

17.3. 1 Why Are Nutritional Values of Proteins Classified?

The nutritional values of proteins are classified based on the following factors:

  • Protein Efficiency Ratio (PER)
  • Biological Value (BV)
  • Net Protein Utilization (NPU)
  • Chemical Value

Protein Requirements: The requirement for protein intake, its nutritional value, and calorie needs depend on various factors, including physiological conditions like growth, pregnancy, and lactation.

  • For adults, 0.8 to 1.0 grams of protein per kilogram of body weight per day is

sufficient.

  • Growing children, pregnant women, and lactating women require roughly double the

amount of protein compared to adults. Recommended dosages in food Protein - 1.2 g / kg /1 day of which at least 50 percent should be high quality protein. Calorie- 35 kcal/kg/1 for those less than 60 years 30-35 kcal/kg/1 day for those 60 years or older Total Fat- 25 %-35 % of total power 25-35 % Saturated Fat ­ <7% Sodium (salt)- 80-100 ml mol Potassium - < 1 mmol/kg Cholesterol - < 200 mg if overdose Total fiber- 20-30 g / 1 day Food Sources of Protein:

  • The amount of protein in food varies depending on the type of diet: o Cereals: 6-12% o Legumes: 18-22% o Meat: 18-25% o Eggs: 10-14% o Milk: 3-4% o Vegetables: 1-2%
  • Proteins in meat are higher than those found in vegetables.

Recommended Daily Allowance (RDA):

  • The Recommended Dietary Allowances (RDA) indicate the amount of nutrients that should be included in the diet to maintain health and physical performance.
  • The RDA for men is 20% higher than for women.

Chronic Kidney Disease and Protein Intake:

  • Protein is essential for building muscle, repairing tissue, and fighting infection.
  • However, if you have kidney disease, it's important to monitor your protein intake. Too much protein can lead to the accumulation of waste in your digestive system, and your kidneys may struggle to remove the excess waste, potentially causing kidney damage.

Dietary Guidelines for Chronic Kidney Disease:

  • Daily protein intake: 0.6 - 0.8 grams per kilogram of body weight
  • Calorie intake: 30 - 35 kcal per kilogram of body weight
  • Fat: Less than 30% of total energy intake from fat
  • Fiber: 25 to 38 grams per day
  • Salt: 2 to 3 grams per day
  • Potassium: Potassium intake should be limited in the diet depending on the amount of bleeding.
  • Calcium: 1500 mg of calcium per day.
  • Phosphorus: 0.8 to 1 gram of phosphorus per day.

Medical Nutrition Therapy: Six types of nutrients are regulated:

  • Protein
  • Sodium
  • Potassium
  • Phosphorus
  • Calcium
  • Fluid Volume

Recommended Dose of Potassium:

  • Patients undergoing peritoneal and hemodialysis require a protein intake of 1.0 - 1.2 g/kg body weight per day.
  • For chronic kidney patients who have not yet started dialysis, a protein intake of 0.6 to 0.8 g/kg/day is recommended.
  • For chronic kidney disease stage 1 and 2, it is now recommended to limit dietary protein to no more than 0.8 grams per kilogram of body weight.

BMI (kg/m2) Category / Energy Requirements kcal/kg/d Body Mass Index Category Required Caloric Intake 35 ­ 40 < 15 30 ­ 35 15 ­ 19

20 ­ 29 20 ­ 25

>30 15-20

Recommended daily protein intake Protein Requirement (grams per kilogram of ideal body weight per day) Medical Condition 0.75

Healthy Condition: 1.0 ­ 1.5 Surgery, Accidents, and Other

1.2 ­ 1.4

Critical Situations: 1.3 ­ 1.5 Blood Purification: Peritoneal Dialysis:

Continuous Dialysis / Obesity: 1.7 ­ 2.0

17.4 Sodium and its Sources Sodium and Kidney Disease:

Salt Intake

  • Sodium is an important mineral naturally present in our bodies.
  • It helps maintain blood pressure and fluid balance.
  • For dialysis patients, doctors and dietitians recommend reducing the amount of salt

in the diet, depending on the individual's sodium levels.

  • Common salt is called sodium.

17.4. 1 Where is Sodium Transported From?

  • Sodium is naturally present in most foods.
  • Table salt contains about 40% sodium and 60% chloride.
  • Sodium is often added to processed foods to preserve or enhance flavor.
  • This salt is found in highly processed, frozen vegetables, cured meats, and pickles.
  • It is used in butter, cheese, bread, salad dressings, and many other breakfast foods.

17.4. 2 How is Curing Salt Used?

  • Salt is used in various ways in the diet, especially in processed foods.
  • Manufacturers of prepared, frozen, and processed foods often use sodium to

enhance the flavor of their products.

  • Sodium plays an important role in food security and as a material in food

preservation. Sodium's Role in the Body:

  • Regulates blood pressure and blood volume.
  • Aids in muscle movement.
  • Regulates acid-base balance of blood and body fluids.
  • Maintains intracellular water balance.
  • Consuming too much sodium can lead to leg swelling or water retention.
  • The normal range for sodium is 135 - 145 mEq/liter.

17.4. 3 How Does Sodium Affect People with Kidney Disease?

  • If you have kidney disease, your kidneys may be unable to remove excess sodium and

fluid from your body.

  • Increased blood pressure and elevated sodium and fluid levels can make you feel

unwell.

  • This can lead to high blood pressure, potentially causing further damage to already unhealthy kidneys.
  • Ongoing kidney damage reduces kidney function, leading to more fluid and waste retention in the body. Symptoms of this condition develop as a result.

Problems Caused by High Sodium Intake:

  • Heart failure
  • Swelling in hands and feet
  • Shortness of breath

Sodium Recommendations by the World Health Organization (WHO):

  • Maximum sodium intake should be 2 g/day.
  • Sodium in salt is 2.5g per 5g of salt.

These recommendations may vary based on your health status. Points to Note:

  • Use common salt in proper quantities.
  • Avoid using "lona" salt.
  • Do not add salt while cooking or at the table.
  • You can add flavoring and sodium-free spices to your food.
  • Try to avoid fast food.

FDA-Approved Sodium Content in Food:

  • Sodium-Free Food ­ Only a very small amount of sodium per serving.
  • Very Low Sodium ­ 35 mg or less per serving.
  • Low Sodium ­ 140 mg or less per serving.
  • Reduced Sodium ­ Foods with 25% less sodium.
  • Light in Sodium ­ Foods with at least 50% sodium reduction.

17.4. 4 Sodium-Rich Foods:

  • Processed meats
  • Processed, frozen, or canned foods
  • Cheese, butter, sauces, breads, pasta mixes
  • Commercial rice varieties
  • Meals served in restaurants, processed foods, and packaged foods are usually high in sodium.
  • Smoked meats, sea fish
  • Confections like Rolled Chub, Salted Ilkut, Salted Popcorn, Namkans
  • Baking soda, sodium bicarbonate, sodium benzoate
  • Varieties of pickles
  • Salted food additives like ready-made masalas
  • Dry fruits and nuts
  • Beverages such as cold drinks, energy drinks, chocolate drinks, and pudding mixes
  • Animal meats like pork, ham, lamb, etc.

17.5 Potassium

Potassium is another essential mineral found in the foods you eat. It is also an electrolyte, which conducts electrical impulses throughout the body. Potassium plays a crucial role in the body's vital functions, including:

  • Blood pressure regulation
  • Normal water balance
  • Muscle movement
  • Nerve function
  • Digestion and bowel movements
  • Heart rate
  • Acidity/alkalinity balance

Your body naturally produces potassium, but it is important to consume the right amount of potassium-rich foods and drinks. Blood Levels of Potassium:

  • Normal level: 3.5 to 5.0 mEq/L
  • High level: 5.1 to 6.0 mEq/L
  • Dangerously high level: Above 6.0 mEq/L Potassium Level (MEq/L)

Normal Range: 3.5 - 5.0

High Range: 5.1 - 6.0

Dangerously High Range: > 6.0

Foods Rich in Potassium:

  • Dry fruits and nuts
  • Blackcurrant, jaggery, jam
  • Black tea, black coffee, fruit juices, squashes, and bottled drinks
  • Coconut water and related foods
  • Squashes, ketchup, and canned foods
  • Pudina chutney and coconut chutney
  • Green vegetables, such as green salads
  • Ragi and its products
  • All types of soups.
  • Fruits High in Potassium: Orange, Mango, Banana, Pomegranate, Date
  • Avocado, Dried Apricot, Gooseberry
  • Potatoes

Helpful Tips to Reduce Potassium Levels in Your Diet:

  1. Vegetables: Wash and peel vegetables, then soak them in boiled water for at least 30 minutes. After soaking, filter the water and cook the vegetables by boiling them in fresh water. Discard the cooking water.
  2. Fruits: Most fruits are high in potassium. Opt for fruits such as apple, guava, papaya, and pear, which are lower in potassium. Limit intake to 2-3 pieces per day.
  3. Spices: Since spices are high in potassium, reduce their use.

Vegetables High in Potassium:

  • Amaranth
  • Coriander leaves
  • Coast types
  • Potatoes
  • Sweet potatoes
  • Tapioca
  • Drumstick
  • Eggplant
  • Tomatoes

Vegetables Low in Potassium:

  • Fenugreek leaves
  • Yellow squash
  • Zucchini
  • Broad beans
  • Cucumber
  • Thread col
  • Peas
  • Ridge Gourd
  • Snake Gourd
  • Chow Chow

Fruits High in Potassium:

  • Mango
  • Sapota
  • Paddy
  • Melon
  • Pomegranate
  • Red banana
  • Dates

Fruits Low in Potassium:

  • Apple
  • Papaya
  • Guava
  • Watermelon

Nuts High in Potassium:

  • Almonds
  • Pistachio nuts
  • Pumpkin seeds
  • Flax seeds
  • Brazil nuts
  • Dried, roasted peanuts

Nuts Low in Potassium:

  • Walnuts
  • Cashew nuts

Phosphorus Levels: Phosphorus is absorbed into the blood by the kidneys and helps maintain the body's normal acid/alkaline balance. Increased blood levels of phosphorus during renal failure can lower calcium levels in the peripheral blood, leading to weak bones. Phosphorus is found in many foods. In healthy kidneys, it is excreted in urine efficiently. However, in renal failure, phosphorus levels can rise, leading to issues such as:

  • Muscle aches and cramps
  • Weakening of bones, making them brittle
  • Heart, skin, joints and clotting of calcium in blood vessels
  • Usually, 1000 mg per day in your diet. Only phosphorus is present. It is best to cut

down on foods high in phosphorus. Avoid high-phosphorus foods that include:

  • Dairy products
  • Dry beans and lentils
  • Cured meats, red meat
  • Pork, beef
  • Fatty fish, and shellfish
  • Milk, yogurt, cheese, yeast varieties
  • Dry fruits and vegetables
  • Dark chocolates
  • Carbonated cola drinks

Liquids:

Liquids don't just mean water. Your kidneys' main job is to remove waste from the body. With a well-functioning urinary system, excess water is excreted through the urine. Since your kidneys are very active, they can excrete the required amount of fluid according to the body's functions and store it in the right amount. This is an amazing performance.

When kidney function declines, it becomes unable to remove excess fluid. So, there is a risk of excess fluid in your body. For people with kidney problems and those undergoing dialysis, the amount of urine output will be greatly reduced. So, the fluid in the body increases and can be dangerous.

Unexpected Problems May Appear:

  • Swelling all over the body
  • Shortness of breath
  • Increase in blood pressure
  • Weight gain

General Notes:

  • If the amount of thiram in the body is too low, the blood pressure may decrease. This also stresses the kidneys further.
  • Water is an important nutrient. The kidneys play an important role in regulating this fluid balance in our body.
  • In between sessions on dialysis, patients are expected to gain some weight due to the increased water content in the foods they eat.
  • Dialysis removes waste from the body and prevents excess fluid from accumulating in the body.
  • You should be careful about your total fluid intake. Note that tea, milk, rice flour, water, and any other liquid form (including thin sambar, rasam, buttermilk) are included in the calculation.
  • Count frozen foods that thaw at room temperature as additional data.
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Chapter 18

Chapter 18

Frequently Asked Questions

18.1 What is the Best Diet for People with Kidney Problems?

Dialysis patients should include more protein in their diet. High-quality proteins reduce the accumulation of excess waste salts in the blood. Lamb, chicken, fish, and egg whites are good sources of lean protein. Non-meat eaters can add milk, chickpeas, and pulses for more protein.

18.2 Why is Diet Important for Kidney Damage?

Adopting a kidney-healthy diet can not only improve your kidney function but also slow down the rate of kidney failure. It also helps in reducing the risk of complications. This diet prevents your body from accumulating too many minerals due to the kidneys not working properly.

18.3 Which Nutrients Should Be Avoided in the Diet If There is Kidney Damage?

People with kidney problems need to cut sodium, potassium, and phosphorus from their diet. Your dietary restrictions and portions can be altered according to your individual needs, at your doctor's office or it's best to consult with a dietitian who specializes in dialysis and create a personalized plan.

18.4 What Types of Foods Can Harm Your Kidneys? Why?

Avoid eating processed foods. Processed foods are high in salt (sodium), and many studies have shown that excess phosphorus in processed foods can be harmful to the kidneys and bones of people with kidney disease. It is important to avoid overdoing it and ensure that your diet is balanced and kidney-friendly.

18.5 What Are the Dietary Restrictions for Dialysis Patients?

It is recommended to reduce potassium-rich fruits, vegetables, legumes, and dairy products. Phosphoric acid also needs to be controlled in the diet because it cannot be effectively filtered out of the blood through dialysis.

18.6 Why Do Dialysis Patients Need Protein in Their Diet?

After a person starts undergoing dialysis, it becomes necessary to include more protein in the diet to keep the protein levels in the blood from decreasing. It helps protect overall health. Since protein wastes are removed from the blood during dialysis, there is no need to reduce serum creatinine levels as before starting dialysis.

18.7 Can Kidney Patients Eat Rice?

Rice plays an important role in the diet for kidney damage. Not only does it provide adequate energy to the body, but it also contains essential minerals. A lower dose may benefit people on dialysis.

18.8 How Can Dietary Changes Improve Kidney Function?

What you eat and drink helps balance salt and minerals in your body, contributing to better health and well-being. Eating a recommended healthy diet, with careful management of sodium, potassium, and phosphorus intake, can help prevent and reduce other side effects of kidney disease.

18.9 What Are the Five Nutrients Involved in Kidney Damage?

Here are the highlights of a diet for kidney damage:

  • Nutrients: It is crucial to consume protein-rich foods in the right amounts.
  • Salt: Excess salt or its sodium content in the diet can raise blood pressure, potentially affecting the heart and lungs. Therefore, reducing salt intake is recommended.
  • Potassium: Since potassium is abundant in salty foods, it is important to monitor and adjust the diet accordingly.
  • Phosphorus: It is best to avoid foods that are high in phosphorus.

Calcium:

Calcium is essential for the strength and growth of bones in the body. Eat calcium-rich foods. As many people are prone to low calcium excretion during kidney disease, doctors may also prescribe calcium and vitamin D tablets to correct this.

18.10 What Foods Can Worsen Kidney Damage?

Indigestible, high-protein meats and dairy products can lead to urinary coagulation problems. This puts additional strain on the kidneys to eliminate waste products. Highprotein foods not only contribute to urinary tract infections but can also exacerbate existing kidney issues.

18.11 Can Kidney Patients Eat Tomatoes?

Tomatoes should be restricted in the diet of people with early kidney disease and those who have undergone kidney transplant surgery. If your blood test results show high potassium levels, your doctor and urologist will provide guidance. Depending on the quantity of tomatoes in your diet, potassium becomes an important factor to manage.

18.12 What Are the Dietary Recommendations for Potassium Control in Renal Patients?

To control excess potassium levels, avoid foods high in potassium such as bananas, avocados, and dried nuts.

Here's the neat translation as requested:

Try adding fruits and vegetables to your diet. It is better to boil well-washed, peeled vegetables and stems in water, drain the water, and then cook and eat them.

18.13 What Type of Diet is Recommended for People with Kidney Failure?

A diet low in sodium, salt, potassium, and protein is considered a kidney-healthy diet. Additionally, it's best to consume high-quality proteins. Sometimes, it is necessary to control the amount of water consumed. Potassium and phosphorus may need to be reduced depending on the individual's condition. Dietary advice will vary based on each person's blood levels of these nutrients.

18.14 What Can Kidney Patients Do? What Not to Do?

Can Do Cannot Do

Ensure proper fluid balance. Fluid levels in the body should not become excessive.

Include fruits and vegetables that Stop smoking. are not harmful to the kidneys in your diet..

Use natural ingredients in cooking. Reduce the amount of sugar and salt in your diet.

Exercise regularly. Avoid drinking alcohol.

18.15 What Type of Diet is Suitable for Stage Four Kidney Disease (CKD - Stage 4)?

  • Take pre-cooked foods rather than processed foods.
  • Eat meat, chicken, and fish in small quantities.
  • Avoid salty foods.
  • Avoid refined sugar and high-fat foods.
  • Avoid the habit of drinking alcohol, etc.

18.16 Why is Water Intake Restricted for Affected People?

If too much water accumulates in your body, it will not only cause swelling in your hands and feet but also lead to difficulty in breathing. When you're on dialysis, your body can't completely flush out the water it needs and maintain the proper balance. That is why this restriction is necessary.

18.17 Why is the Amount of Salt in the Diet Reduced for People with Kidney Problems?

People with kidney disease should pay close attention to the amount of salt in their recommended diet. Excess salt not only increases blood pressure but can also worsen hypertension, which can be dangerous.

18.18 How Much Protein Can a Healthy Person Consume Per Day?

An average healthy person needs 1 gram of protein per 1 kg of body weight per day. For example, if a person weighs 75 kg, they can consume 75 grams of protein per day.

18.19 Why Should Protein Content Be Reduced in the Diet of People with Kidney Disease?

When the kidneys are not functioning properly, waste products such as urea from protein build up in the blood. This leads to loss of appetite, tiredness, and fatigue due to nitrogen imbalance and damaged kidneys. The need to excrete waste products in the urine is reduced. Therefore, reducing protein intake helps protect the unaffected parts of the kidney from overworking and helps prevent kidney damage from worsening too quickly.

18.20 What is a Common Diet Suitable for People with Kidney Problems?

It is very important for people with kidney disease to make necessary changes in their diet. Drink less water and increase protein intake cautiously. Reduce foods containing minerals like salt, potassium, and phosphorus. It is also important to consume the required number of calories to prevent weight loss.

18.21 Can Susceptible People Add Salt to Their Food?

It is better to add normal salt in the required quantity. Avoid using Himalayan salt, as it contains more potassium instead of sodium.

18.22 Is the Salt That is Said to Be Excessive During Kidney Problems and the Salt That We

Include in Our Daily Diet the Same?

No. Creatinine refers to the amount of salt that has been processed during the urinary tract. The salt added to our food is called sodium (common salt). There is no relationship between the amount of salt processed in the urinary tract and the amount of salt added to the diet. Therefore, reducing salt too much in the diet without a doctor's advice can be dangerous. Avoiding salt completely without consulting a doctor or dietitian is a mistake. Remember:

  1. Kidney damage can occur without any symptoms. So, get your kidney health checked.
  1. Diabetes and high blood pressure increase the chances of developing urinary retention. Therefore, people with these conditions need more attention.
  1. Not all kidney disorders require dialysis. If detected at an early stage, they can be corrected through medical intervention, dietary modifications, and lifestyle changes.
  1. Not all patients require continuous dialysis treatment. Severe sudden renal failure may only require 2 or 3 weeks of dialysis.
  1. If end-stage chronic renal failure is reached, continuous dialysis should be considered or kidney transplantation may be an option.
  1. Abdominal dialysis is also an excellent treatment method and allows individuals to live normally.
  1. Transplant patients should avoid crowded places where infections may occur. Immunosuppressive medications should be taken regularly
  2. Remember the Eight Golden Rules:
  3. Control diabetes
  4. Maintain proper blood pressure
  5. Reduce obesity
  6. Exercise regularly
  7. Pay attention to diet
  8. Avoid smoking
  9. Avoid drinking alcohol
  10. Do not take pills directly without a doctor's advice Let's maintain kidney health. Let's live happily.
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23, B,Salem Gopi Hospital, Ramakrishna Rd,
Hasthampatti, Salem, Tamil Nadu 636007

+91 9894352229
0427 266 6444
salemgopihosp@gmail.com

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